Mammalian dentition consists of teeth that develop as discrete organs. From anterior to
posterior, the dentition is divided into regions of incisor, canine, premolar and molar tooth …

This review focuses on the process of enamel maturation, a series of events associated with
slow, progressive growth in the width and thickness of apatitic crystals. This developmental …

The biomineralization of the dental enamel matrix with a carbonated hydroxyapatite mineral
generates one of the most remarkable examples of a vertebrate mineralized tissue. Recent …

Biochemical investigations in rodents have shown that numerous mineralized matrix
proteins share expression in bone, dentin, and cementum. Little information is available …

The integument forms a number of different types of mineralized element, including dermal
denticles, scutes, ganoid scales, elasmoid scales, fin rays and osteoderms found in certain …

Sp3 is a ubiquitously expressed transcription factor closely related to Sp1 (specificity protein
1). We have disrupted the mouse Sp3 gene by homologous recombination. Sp3‐deficient …

Enamel is a complex bioceramic tissue. In its final form, enamel is a reflection of the unique
molecular and cellular activities occurring during organogenesis. From the ectodermal …

Substantial advancements have been made in defining the cells and molecular signals that
guide tooth crown morphogenesis and development. As a result, very encouraging progress …

Mineralized tissues are unique in using proteins to attract and organize calcium and
phosphate ions into a structured mineral phase. A precise knowledge of the expression and …

Amelogenin is the major enamel protein produced by ameloblasts. Its expression has been
shown to be down-regulated in ameloblasts of vitamin-D-deficient (− D) rats. The potential …