1962). Indeed, the two membranes are separated by a Calcium plays an important role in
regulating a great fuzzy material with a distinct periodicity reminiscent of variety of neuronal …

The inositol 1, 4, 5-trisphosphate (InsP3) receptors (InsP3Rs) are a family of Ca2+ release
channels localized predominately in the endoplasmic reticulum of all cell types. They …

Mitochondria are central to energy metabolism as the source of much of the cell's ATP, as
well as being a hub for cellular Ca 2+ signaling. Mitochondrial Ca 2+ is a positive effector of …

Abstract Inositol 1, 4, 5‐trisphosphate (IP3) is a second messenger that induces the release
of Ca2+ from the endoplasmic reticulum (ER). The IP3 receptor (IP3R) was discovered as a …

Ca2+ release from inositol 1, 4, 5-trisphosphate (IP3)-sensitive and ryanodine-sensitive
intracellular Ca2+ stores is mediated by distinct proteins identified as IP3 receptors (IP3R) …

Serological testing for anti-neural autoantibodies is important in patients presenting with
idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine …

Mitochondria have long been known to accumulate Ca2+; the apparent inconsistency
between the low affinity of mitochondrial Ca2+ uptake mechanisms, the low concentration of …

Abstract IP 3 receptor (IP 3 R) was found to release Ca 2+ from non-mitochondrial store but
the exact localization and the mode of action of IP 3 remained a mystery. IP 3 R was …

Background Taste receptor cells are responsible for transducing chemical stimuli into
electrical signals that lead to the sense of taste. An important second messenger in taste …

Abstract Inositol 1, 4, 5‐trisphosphate receptors (IP3R) are mediators of second messenger‐
induced intracellular calcium release. Three isoforms are known to be expressed in brain …