Insights into epileptogenesis from post-traumatic epilepsy
Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …
Early seizure prophylaxis in mild and moderate traumatic brain injury: a systematic review and meta-analysis
Importance Guidelines recommend seizure prophylaxis for early posttraumatic seizures
(PTS) after severe traumatic brain injury (TBI). Use of antiseizure medications for early …
(PTS) after severe traumatic brain injury (TBI). Use of antiseizure medications for early …
Predicting posttraumatic epilepsy using admission electroencephalography after severe traumatic brain injury
Objective Posttraumatic epilepsy (PTE) develops in as many as one third of severe traumatic
brain injury (TBI) patients, often years after injury. Analysis of early electroencephalographic …
brain injury (TBI) patients, often years after injury. Analysis of early electroencephalographic …
Early post‐traumatic seizures in hospitalized patients with traumatic brain injury
HF Sødal, G Storvig, C Tverdal… - Acta Neurologica …, 2022 - Wiley Online Library
Objectives Early post‐traumatic seizures (EPTS) are a well‐known complication of traumatic
brain injury (TBI). EPTS increase the risk of secondary brain injury and may cause significant …
brain injury (TBI). EPTS increase the risk of secondary brain injury and may cause significant …
[HTML][HTML] Seizure susceptibility and sleep disturbance as biomarkers of epileptogenesis after experimental TBI
P Andrade, L Lara-Valderrábano, E Manninen… - Biomedicines, 2022 - mdpi.com
Objectives: We investigated whether seizure susceptibility increases over weeks–months
after experimental traumatic brain injury (TBI), and whether seizure susceptibility in rats …
after experimental traumatic brain injury (TBI), and whether seizure susceptibility in rats …
Posttraumatic Epilepsy and Dementia Risk
ALC Schneider, CA Law, RF Gottesman… - JAMA …, 2024 - jamanetwork.com
Importance Although both head injury and epilepsy are associated with long-term dementia
risk, posttraumatic epilepsy (PTE) has only been evaluated in association with short-term …
risk, posttraumatic epilepsy (PTE) has only been evaluated in association with short-term …
Levetiracetam pharmacokinetics and brain uptake in a lateral fluid percussion injury rat model
LD Coles, PG Saletti, CP Lisgaras… - … of Pharmacology and …, 2023 - ASPET
Post-traumatic epilepsy (PTE) occurs in some patients after moderate/severe traumatic brain
injury (TBI). Although there are no approved therapies to prevent epileptogenesis …
injury (TBI). Although there are no approved therapies to prevent epileptogenesis …
[HTML][HTML] Adolescent traumatic brain injury leads to incremental neural impairment in middle-aged mice: role of persistent oxidative stress and neuroinflammation
Z Chen, P Wang, H Cheng, N Wang, M Wu… - Frontiers in …, 2023 - frontiersin.org
Background Traumatic brain injury (TBI) increases the risk of mental disorders and
neurodegenerative diseases in the chronic phase. However, there is limited …
neurodegenerative diseases in the chronic phase. However, there is limited …
International survey of antiseizure medication use in patients with complicated mild traumatic brain injury: a New York Neurotrauma Consortium Study
ZL Hickman, LA Spielman, EJ Barthélemy… - World Neurosurgery, 2022 - Elsevier
Background Seizures and epilepsy after traumatic brain injury (TBI) negatively affect quality
of life and longevity. Antiseizure medication (ASM) prophylaxis after severe TBI is associated …
of life and longevity. Antiseizure medication (ASM) prophylaxis after severe TBI is associated …
EEG biomarkers for the prediction of post-traumatic epilepsy-a systematic review of an emerging field
J Pyrzowski, M Kałas… - … : European Journal of …, 2024 - Elsevier
Traumatic brain injury (TBI) is often followed by post-traumatic epilepsy (PTE), a condition
often difficult to treat and leading to a substantial decline in quality of life as well as …
often difficult to treat and leading to a substantial decline in quality of life as well as …