The human gastrointestinal tract, boasting the most diverse microbial community, harbors
approximately 100 trillion microorganisms comprising viruses, bacteria, fungi, and archaea …

Neurodegenerative diseases encompass a spectrum of disorders marked by the
progressive degeneration of the structure and function of the nervous system. These …

Stress and circadian systems are interconnected through the hypothalamic-pituitary-adrenal
(HPA) axis to maintain responses to external stimuli. Yet, the mechanisms of how such …

Cancer neuroscience, a promising field dedicated to exploring interactions between cancer
and the nervous system, has attracted growing attention. The gastrointestinal tracts exhibit …

Diabetic encephalopathy (DE), characterized by cognitive impairment, currently lacks
targeted treatment. Previous studies have shown that Sarcandra glabra extracted residue …

Increasing evidence suggests that the gut microbiome plays a key role in a host of
pathological conditions, including cancer. Indeed, the bidirectional communication that …

Amyotrophic lateral sclerosis (ALS) is the most common form of human motor neuron
disease. It is characterized by the progressive degeneration of upper and lower motor …

Background Lingguizhugan (LGZG) decoction, an ancient Chinese herbal remedy
originating from the Eastern Han Dynasty, consists of Poria cocos, Cinnamomi ramulus …

Stroke is one of the most devastating pathologies in terms of mortality, cause of dementia,
major adult disability, and socioeconomic burden worldwide. Despite its severity, treatment …

Background: The gut barrier is a sophisticated and dynamic system that forms the frontline
defense between the external environment and the body's internal milieu and includes …