Metformin improves ovarian cancer sensitivity to paclitaxel and platinum-based drugs: a review of in vitro findings

G Tossetta - International Journal of Molecular Sciences, 2022 - mdpi.com
Ovarian cancer is one of the most dangerous gynecologic cancers worldwide, showing a
high fatality rate and recurrence due to diagnosis at an advanced stage of the disease and …

Non-coding RNAs targeting notch signaling pathway in cancer: From proliferation to cancer therapy resistance

M Hashemi, S Hasani, S Hajimazdarany… - International journal of …, 2022 - Elsevier
Cancer is a challenging to treat disease with a high mortality rate worldwide, nevertheless
advances in science has led to a decrease in the number of death cases caused by cancer …

[HTML][HTML] HMGA2 regulation by miRNAs in cancer: affecting cancer hallmarks and therapy response

M Hashemi, M Rashidi, K Hushmandi… - Pharmacological …, 2023 - Elsevier
High mobility group A 2 (HMGA2) is a protein that modulates the structure of chromatin in the
nucleus. Importantly, aberrant expression of HMGA2 occurs during carcinogenesis, and this …

The cross-talk between LncRNAs and JAK-STAT signaling pathway in cancer

A Hjazi, RF Obaid, SS Ali, B Abdullaev… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) are non-coding RNAs that were transcribed from the
human genome and have become important regulators in a number of cellular activities …

[HTML][HTML] Copper overload exacerbates testicular aging mediated by lncRNA: CR43306 deficiency through ferroptosis in Drosophila

Q Huang, J Li, Y Qi, X He, C Shen, C Wang, X Wang… - Redox biology, 2024 - Elsevier
Testicular aging manifests as impaired spermatogenesis and morphological alterations in
Drosophila. Nonetheless, the comprehensive molecular regulatory framework remains …

[HTML][HTML] The role of lncRNAs and exosomal lncRNAs in cancer metastasis

Y Zhang, L Zhao, Y Bi, J Zhao, C Gao, X Si… - Biomedicine & …, 2023 - Elsevier
Tumor metastasis is the main reason for cancer-related death, but there is still a lack of
effective therapeutic to inhibit tumor metastasis. Therefore, the discovery and study of new …

[HTML][HTML] Upregulation of long noncoding RNA MALAT1 in colorectal cancer promotes radioresistance and aggressive malignance

W Shen, Q Yu, Y Pu, C Xing - International journal of general …, 2022 - ncbi.nlm.nih.gov
Background Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a
conserved transcript with 8000 nt, is highly associated with malignancy of numerous cancer …

Cancer-derived exosomes as novel biomarkers in metastatic gastrointestinal cancer

D Zhong, Z Wang, Z Ye, Y Wang, X Cai - Molecular Cancer, 2024 - Springer
Gastrointestinal cancer (GIC) is the most prevalent and highly metastatic malignant tumor
and has a significant impact on mortality rates. Nevertheless, the swift advancement of …

The emerging roles of long non-coding RNA (lncRNA) H19 in gynecologic cancers

M Ghasemian, M Zehtabi, MAG Dari, FK Pour… - BMC cancer, 2024 - Springer
Long non-coding RNA (lncRNA) H19 has gained significant recognition as a pivotal
contributor to the initiation and advancement of gynecologic cancers, encompassing …

LncRNA PKD2-2-3 对肺腺癌细胞增殖, 克隆形成, 迁移及侵袭能力的影响

贾利晴, 葛小路, 姜琳, 周晓燕 - 中国癌症杂志, 2023 - china-oncology.com
背景与目的: 长链非编码RNA (long non-coding RNA, lncRNA) 在肺腺癌患者中异常表达,
与肿瘤的发生, 发展和化疗耐药密切相关. 本研究旨在探讨lncRNA 蛋白激酶D2 (lncRNA PKD2 …