The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens
are outpacing the development of new antibiotics, but antivirulence agents provide an …

Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …

Bacterial quorum sensing (QS) is a cell‐to‐cell communication in which specific signals are
activated to coordinate pathogenic behaviors and help bacteria acclimatize to the …

Clostridium difficile is a bacterial pathogen that is the leading cause of nosocomial antibiotic-
associated diarrhea and pseudomembranous colitis worldwide. The incidence, severity …

Clostridium difficile infection (CDI) is the leading cause of antimicrobial and health care-
associated diarrhea in humans, presenting a significant burden to global health care …

The pathogenic clostridia cause many human and animal diseases, which typically arise as
a consequence of the production of potent exotoxins. Among the enterotoxic clostridia …

The ribosomally synthesized and posttranslationally modified peptides (RiPPs), also called
ribosomal peptide natural products (RPNPs), form a growing superfamily of natural products …

Quorum sensing (QS), which is a key part of cell/cell communication, is widely distributed in
microorganisms, especially in bacteria. Bacteria can produce and detect the presence of QS …

Clostridium difficile is the prominent etiological agent of healthcare-associated diarrhea. The
disease symptoms range from mild diarrhea to life-threatening pseudomembranous colitis …

Clostridium difficile is the largest single cause of hospital-acquired infection in the United
States. A major risk factor for Clostridium difficile infection (CDI) is prior exposure to …