Advances in resection and transplantation for hepatocellular carcinoma
It would be impossible to summarise all of the significant developments in the surgical
management of hepatocellular carcinoma (HCC), even just over the past year, in a …
management of hepatocellular carcinoma (HCC), even just over the past year, in a …
[HTML][HTML] Normothermic liver machine perfusion as a dynamic platform for regenerative purposes: What does the future have in store for us?
B Lascaris, VE de Meijer, RJ Porte - Journal of Hepatology, 2022 - Elsevier
Liver transplantation has become an immense success; nevertheless, far more recipients
are registered on waiting lists than there are available donor livers for transplantation. High …
are registered on waiting lists than there are available donor livers for transplantation. High …
Ischemia-reperfusion injury in marginal liver grafts and the role of hypothermic machine perfusion: molecular mechanisms and clinical implications
Ischemia-reperfusion injury (IRI) constitutes a significant source of morbidity and mortality
after orthotopic liver transplantation (OLT). The allograft is metabolically impaired during …
after orthotopic liver transplantation (OLT). The allograft is metabolically impaired during …
The future of organ perfusion and re‐conditioning
A Weissenbacher, G Vrakas, D Nasralla… - Transplant …, 2019 - Wiley Online Library
Organ preservation and re‐conditioning using machine perfusion technologies continue to
generate promising results in terms of viability assessment, organ utilization and improved …
generate promising results in terms of viability assessment, organ utilization and improved …
Emerging role of NLRP3 inflammasome and pyroptosis in liver transplantation
F Lucas-Ruiz, A Peñín-Franch, JA Pons… - International journal of …, 2022 - mdpi.com
The nucleotide-binding domain leucine-rich repeat-receptor, pyrin domain-containing-3
(NLRP3) inflammasome contributes to the inflammatory response by activating caspase-1 …
(NLRP3) inflammasome contributes to the inflammatory response by activating caspase-1 …
Review of current machine perfusion therapeutics for organ preservation
J Xu, JE Buchwald, PN Martins - Transplantation, 2020 - journals.lww.com
Because of the high demand of organs, the usage of marginal grafts has increased. These
marginal organs have a higher risk of developing ischemia-reperfusion injury, which can …
marginal organs have a higher risk of developing ischemia-reperfusion injury, which can …
Normothermic machine perfusion (NMP) of the liver as a platform for therapeutic interventions during ex-vivo liver preservation: a review
F Dengu, SH Abbas, G Ebeling, D Nasralla - Journal of clinical medicine, 2020 - mdpi.com
Liver transplantation is increasingly dependent on the use of extended criteria donors (ECD)
to increase the organ donor pool and address rising demand. This has necessitated the …
to increase the organ donor pool and address rising demand. This has necessitated the …
[HTML][HTML] RNA interference therapeutics in organ transplantation: The dawn of a new era
IMA Brüggenwirth, PN Martins - American Journal of Transplantation, 2020 - Elsevier
RNA interference (RNAi) is a natural process through which double-stranded RNA
molecules can silence the gene carrying the same code as the particular RNA of interest. In …
molecules can silence the gene carrying the same code as the particular RNA of interest. In …
[HTML][HTML] Normothermic machine perfusion (NMP) of the liver–current status and future perspectives
CJ van Beekum, TO Vilz, TR Glowka… - Annals of …, 2021 - ncbi.nlm.nih.gov
A shortage of available organs for liver transplantation has led transplant surgeons and
researchers to seek for innovative approaches in hepatoprotection and improvement of …
researchers to seek for innovative approaches in hepatoprotection and improvement of …
Normothermic machine perfusion systems: where do we go from here?
S López-Martínez, C Simón, X Santamaria - Transplantation, 2024 - journals.lww.com
Normothermic machine perfusion (NMP) aims to preserve organs ex vivo by simulating
physiological conditions such as body temperature. Recent advancements in NMP system …
physiological conditions such as body temperature. Recent advancements in NMP system …