Heart failure (HF) is a significant cause of morbidity and mortality worldwide. Circulating
biomarkers reflecting pathophysiological pathways involved in HF development and …

Congestion is a cardinal sign of heart failure (HF). In the past, it was seen as a
homogeneous epiphenomenon that identified patients with advanced HF. However, current …

Episodes of worsening symptoms and signs characterize the clinical course of patients with
chronic heart failure (HF). These events are associated with poorer quality of life, increased …

Congestion explains many of the signs and symptoms of acute heart failure (AHF) and
disease progression. However, accurate quantification of congestion is challenging in daily …

Interest in the pathophysiology, etiology, management, and outcomes of patients with
tricuspid regurgitation (TR) has grown in the wake of multiple natural history studies showing …

Aims Albuminuria is common in patients with heart failure and associated with worse
outcomes. The underlying pathophysiological mechanism of albuminuria in heart failure is …

Congestion plays a major role in the pathogenesis, presentation, and prognosis of heart
failure and is an important therapeutic target. However, its severity and organ and …

Aims Inflammation is thought to play a role in heart failure (HF) pathophysiology. Neutrophil‐
to‐lymphocyte ratio (NLR) is a simple, routinely available measure of inflammation. Its …

Background Congestion is the main driver behind symptoms of heart failure (HF), but
pathophysiology related to congestion remains poorly understood. Objectives Using …

ABSTRACT Point-of-Care Ultrasonography (PoCUS) aims to include a fifth pillar
(insonation) in the classical physical examination in order to obtain images to answer …