A systematic review of closed head injury models of mild traumatic brain injury in mice and rats

CN Bodnar, KN Roberts, EK Higgins… - Journal of …, 2019 - liebertpub.com
Mild TBI (mTBI) is a significant health concern. Animal models of mTBI are essential for
understanding mechanisms, and pathological outcomes, as well as to test therapeutic …

Laser speckle imaging to monitor microvascular blood flow: a review

PG Vaz, A Humeau-Heurtier, E Figueiras… - IEEE reviews in …, 2016 - ieeexplore.ieee.org
Laser speckle is a complex interference phenomenon that can easily be understood, in
concept, but is difficult to predict mathematically, because it is a stochastic process. The use …

Intrinsic, widefield optical imaging of hemodynamics in rodent models of Alzheimer's disease and neurological injury

C Crouzet, T Phan, RH Wilson, TJ Shin… - …, 2023 - spiedigitallibrary.org
The complex cerebrovascular network is critical to controlling local cerebral blood flow
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …

Optically derived metabolic and hemodynamic parameters predict hippocampal neurogenesis in the BTBR mouse model of autism

D Abookasis, D Lerman, H Roth, M Tfilin… - Journal of …, 2018 - Wiley Online Library
In this study, we made use of dual‐wavelength laser speckle imaging (DW‐LSI) to assess
cerebral blood flow (CBF) in the BTBR‐genetic mouse model of autism spectrum disorder …

Decreased cerebral blood flow and hemodynamic parameters during acute hyperglycemia in mice model observed by dual‐wavelength speckle imaging

D Shemesh, N Bokobza, K Rozenberg… - Journal of …, 2019 - Wiley Online Library
In this study, we use dual‐wavelength optical imaging‐based laser speckle technique to
assess cerebral blood flow and metabolic parameters in a mouse model of acute …

Quantification of the effectivity of laser therapy shortly following brain injury via dual-wavelength laser imaging

D Shemesh, O Aburus, G Turgeman… - Optics & Laser …, 2022 - Elsevier
Abstract Treatment of traumatic brain injury, within a few minutes and even before
transportation to the nearest medical facility, can significantly curtail injury severity and even …

Extendable, large-field multi-modal optical imaging system for measuring tissue hemodynamics

C Wang, X Chen, J Hong, L Meng, W Cheng… - Biomedical Optics …, 2020 - opg.optica.org
Simultaneous imaging of multiple hemodynamic parameters helps to evaluate the
physiological and pathological status of biological tissue. To achieve multimodal …

Determination of the complex refractive index segments of turbid sample with multispectral spatially modulated structured light and models approximation

O Meitav, O Shaul, D Abookasis - Journal of Biomedical Optics, 2017 - spiedigitallibrary.org
Spectral data enabling the derivation of a biological tissue sample's complex refractive index
(CRI) can provide a range of valuable information in the clinical and research contexts …

Hybrid optical monitoring setup for biological tissue diagnosis and assessment: Experimental study

O Aburus, D Shemesh, M Ben-Shachar… - Optics …, 2021 - Elsevier
The use of noninvasive multi-parametric imaging platforms to guide pathological diagnosis
and therapeutic procedures can significantly improve clinical outcomes. A hybrid optical …

Intrinsic, widefield optical imaging of hemodynamics in rodent models of Alzheimer's disease and neurological injury

TJ Shin, B Choi - 2023 - spiedigitallibrary.org
The complex cerebrovascular network is critical to controlling local cerebral blood flow
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …