Decoding epitranscriptomic regulation of viral infection: mapping of RNA N6-methyladenosine by advanced sequencing technologies

X Fan, Y Zhang, R Guo, K Yue, G Smagghe… - Cellular & Molecular …, 2024 - Springer
Elucidating the intricate interactions between viral pathogens and host cellular machinery
during infection is paramount for understanding pathogenic mechanisms and identifying …

Down-regulated FTO and ALKBH5 co-operatively activates FOXO signaling through m6A methylation modification in HK2 mRNA mediated by IGF2BP2 to enhance …

M Ye, J Chen, F Lu, M Zhao, S Wu, C Hu, P Yu, J Kan… - Cell & Bioscience, 2023 - Springer
Abstract Background N6-methyladenosine (m6A) modification is the most abundant
reversible methylation modification in eukaryotes, and it is reportedly closely associated with …

[HTML][HTML] Emerging role of N6-methyladenosine RNA modification in regulation of SARS-CoV-2 infection and virus-host interactions

J Liu, L Chen, X Guo, B Zhao, J Jiang - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Since December 2019, the infection caused by Severe Acute Respiratory Syndrome
Coronavirus Type 2 (SARS-CoV-2) has posed an enormous threat to human health security …

An Exploration of the Coherent Effects between METTL3 and NDUFA10 on Alzheimer's Disease

L Yang, X Pang, W Guo, C Zhu, L Yu, X Song… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized primarily by a
decline in cognitive function. However, the etiopathogenesis of AD is unclear. N6 …

Method for the Enrichment of N6-Methyladenosine-Modified Cellular and HIV-1 RNA

T Mishra, S Phillips, L Wu - HIV Protocols, 2024 - Springer
Abstract N 6-methyladenosine (m6A) modification of RNA is an important area in studying
viral replication, cellular responses, and host immunity. HIV-1 RNA contains multiple m6A …

[HTML][HTML] Severely ill COVID-19 patients have altered circulating levels of proteins controlling the epitranscriptome

A Quiles-Jiménez, MML Sousa, C Huse… - The Journal of …, 2023 - ncbi.nlm.nih.gov
We read with great interest the study by Salto-Alejandre et al. showing that SARS-CoV-2
viral load and interferon (IFN)-γ-mediated immunity, crucial in the acute phase of the viral …