Cytosolic Ca 2+ concentration levels fluctuate in an ordered manner along the cell cycle, in
line with the fact that Ca 2+ is involved in the regulation of cell proliferation. Cell proliferation …

The human selenoprotein family contains 25 members that share the common feature of
containing the amino acid, selenocysteine (Sec). Seven selenoproteins are localized to the …

Cancer, the second cause of death worldwide, is characterized by several common criteria,
known as the “cancer hallmarks” such as unrestrained cell proliferation, cell death …

Protein misfolding is prominent in early cellular pathology of Alzheimer's disease (AD),
implicating pathophysiological significance of endoplasmic reticulum stress/unfolded protein …

Many of the 25 members of the selenoprotein family function as enzymes that utilize their
selenocysteine (Sec) residues to catalyze redox-based reactions. However, some …

An endoplasmic reticulum (ER)‐resident protein that regulates cytosolic and ER free‐Ca2+
concentration by induction of store‐operated calcium entry: that is the original definition of …

Simple Summary The common activation of the c-Myc oncogene in colorectal cancer (CRC)
induces the overexpression of ornithine decarboxylase (ODC), the limiting step in polyamine …

Colorectal cancer (CRC) is the third most frequent form of cancer and the fourth leading
cause of cancer-related death in the world. Basic and clinical data indicate that aspirin and …

Colorectal cancer (CRC) cells undergo the remodeling of intracellular Ca2+ homeostasis,
which contributes to cancer hallmarks such as enhanced proliferation, invasion and survival …

Precise intracellular calcium signaling is crucial to numerous cellular functions. In non-
excitable cells, store-operated calcium entry (SOCE) is a key step in the generation of …