Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications
Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …
among the most frequent causes of disability and death worldwide. Current treatment …
The emerging role of irisin in cardiovascular diseases
J Fu, F Li, Y Tang, L Cai, C Zeng, Y Yang… - Journal of the American …, 2021 - Am Heart Assoc
Irisin, a novel hormone like polypeptide, is cleaved and secreted by an unknown protease
from a membrane‐spanning protein, FNDC5 (fibronectin type III domain‐containing protein …
from a membrane‐spanning protein, FNDC5 (fibronectin type III domain‐containing protein …
Meteorin-like/Metrnl, a novel secreted protein implicated in inflammation, immunology, and metabolism: A comprehensive review of preclinical and clinical studies
Z Li, Z Gao, T Sun, S Zhang, S Yang, M Zheng… - Frontiers in …, 2023 - frontiersin.org
Meteorin-like, also known as Metrnl, Meteorin-β, Subfatin, and Cometin, is a novel secreted
protein exerting pleiotropic effects on inflammation, immunology, and metabolism. Earlier …
protein exerting pleiotropic effects on inflammation, immunology, and metabolism. Earlier …
The adipose-derived mesenchymal stem cell secretome promotes hepatic regeneration in miniature pigs after liver ischaemia-reperfusion combined with partial …
Z Jiao, Y Ma, Q Zhang, Y Wang, T Liu, X Liu… - Stem Cell Research & …, 2021 - Springer
Background Hepatic ischaemia-reperfusion injury (HIRI) is inevitable in complicated liver
surgery and is a major factor leading to postoperative complications and liver dysfunction …
surgery and is a major factor leading to postoperative complications and liver dysfunction …
mTOR pathway–a potential therapeutic target in stroke
K Melanis, MI Stefanou… - Therapeutic …, 2023 - journals.sagepub.com
Stroke is ranked as the second leading cause of death worldwide and a major cause of long-
term disability. A potential therapeutic target that could offer favorable outcomes in stroke is …
term disability. A potential therapeutic target that could offer favorable outcomes in stroke is …
Antioxidant effects of irisin in liver diseases: mechanistic insights
Oxidative stress is a crucial factor in the development of various liver diseases. Irisin, a
metabolic hormone discovered in 2012, is mainly produced by proteolytic cleavage of …
metabolic hormone discovered in 2012, is mainly produced by proteolytic cleavage of …
Effects of intermittent hypoxia on cytokine expression involved in insulin resistance
T Uchiyama, H Ota, C Ohbayashi… - International Journal of …, 2021 - mdpi.com
Sleep apnea syndrome (SAS) is a prevalent disorder characterized by recurrent apnea or
hypoxia episodes leading to intermittent hypoxia (IH) and arousals during sleep. Currently …
hypoxia episodes leading to intermittent hypoxia (IH) and arousals during sleep. Currently …
Notoginseng Triterpenes Inhibited Autophagy in Random Flaps via the Beclin-1/VPS34/LC3 Signaling Pathway to Improve Tissue Survival
Z Huang, X Luo, Y Zhang, Y Ying, X Cai… - … in Bioengineering and …, 2021 - frontiersin.org
Random flaps are widely used in tissue reconstruction, attributed to the lack of vascular axial
limitation. Nevertheless, the distal end of the flap is prone to necrosis due to the lack of blood …
limitation. Nevertheless, the distal end of the flap is prone to necrosis due to the lack of blood …
Sarcopenia is a predictor of patient death in acute ischemic stroke
J Boriesosdick, A Surov, A Michael… - Journal of Stroke and …, 2023 - Elsevier
Background Sarcopenia is proposed as a novel imaging biomarker in several acute
conditions regarding outcome and mortality. The aim of the present study was to investigate …
conditions regarding outcome and mortality. The aim of the present study was to investigate …
[HTML][HTML] Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection
The present review summarizes the beneficial and detrimental roles of reactive oxygen
species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the …
species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the …