Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

Prompt-gamma monitoring in hadrontherapy: A review

J Krimmer, D Dauvergne, JM Létang, É Testa - Nuclear Instruments and …, 2018 - Elsevier
Secondary radiation emission induced by nuclear reactions is correlated to the path of ions
in matter. Therefore, such penetrating radiation can be used for in vivo control of …

A full-scale clinical prototype for proton range verification using prompt gamma-ray spectroscopy

F Hueso-González, M Rabe, TA Ruggieri… - Physics in Medicine …, 2018 - iopscience.iop.org
We present a full-scale clinical prototype system for in vivo range verification of proton pencil-
beams using the prompt gamma-ray spectroscopy method. The detection system consists of …

[HTML][HTML] Range verification methods in particle therapy: underlying physics and Monte Carlo modeling

AC Kraan - Frontiers in oncology, 2015 - frontiersin.org
Hadron therapy allows for highly conformal dose distributions and better sparing of organs-
at-risk, thanks to the characteristic dose deposition as function of depth. However, the quality …

[HTML][HTML] Radioactive beams in particle therapy: past, present, and future

M Durante, K Parodi - Frontiers in physics, 2020 - frontiersin.org
Heavy ion therapy can deliver high doses with high precision. However, image guidance is
needed to reduce range uncertainty. Radioactive ions are potentially ideal projectiles for …

[HTML][HTML] Challenges in Monte Carlo simulations as clinical and research tool in particle therapy: a review

S Muraro, G Battistoni, AC Kraan - Frontiers in Physics, 2020 - frontiersin.org
The use and interest in Monte Carlo (MC) techniques in the field of medical physics have
been rapidly increasing in the past years. This is the case especially in particle therapy …

Spectroscopic study of prompt-gamma emission for range verification in proton therapy

L Kelleter, A Wrońska, J Besuglow, A Konefał… - Physica Medica, 2017 - Elsevier
We present the results of an investigation of the prompt-gamma emission from an interaction
of a proton beam with phantom materials. Measurements were conducted with a novel setup …

Prompt gamma imaging in proton therapy-status, challenges and developments

A Wrońska - Journal of Physics: Conference Series, 2020 - iopscience.iop.org
This paper is an overview of the field of proton therapy monitoring in real time using prompt
gamma radiation. Different approaches providing either integrated or differential information …

On-and off-line monitoring of ion beam treatment

K Parodi - Nuclear Instruments and Methods in Physics Research …, 2016 - Elsevier
Ion beam therapy is an emerging modality for high precision radiation treatment of cancer. In
comparison to conventional radiation sources (photons, electrons), ion beams feature major …

Performance of MACACO Compton telescope for ion-beam therapy monitoring: first test with proton beams

P Solevi, E Munoz, C Solaz, M Trovato… - Physics in Medicine …, 2016 - iopscience.iop.org
In order to exploit the advantages of ion-beam therapy in a clinical setting, delivery
verification techniques are necessary to detect deviations from the planned treatment. Efforts …