Isothermal titration calorimetry (ITC) as a promising tool in pharmaceutical nanotechnology
IDL Cavalcanti, FHX Junior, NSS Magalhães… - International Journal of …, 2023 - Elsevier
Isothermal titration calorimetry (ITC) is a technique for evaluating the thermodynamic profiles
of connection between two molecules, allowing the experimental design of nanoparticles …
of connection between two molecules, allowing the experimental design of nanoparticles …
Dually Active Apigenin-Loaded Nanostructured Lipid Carriers for Cancer Treatment
L Bonilla-Vidal, M Świtalska, M Espina… - International journal …, 2023 - Taylor & Francis
Purpose Cancer is one of the major causes of death worldwide affecting more than 19
million people. Traditional cancer therapies have many adverse effects and often result in …
million people. Traditional cancer therapies have many adverse effects and often result in …
Tuning the elasticity of nanogels improves their circulation time by evading immune cells
Peptide receptor radionuclide therapy is used to treat solid tumors by locally delivering
radiation. However, due to nephro‐and hepato‐toxicity, it is limited by its dosage. To amplify …
radiation. However, due to nephro‐and hepato‐toxicity, it is limited by its dosage. To amplify …
Relevant physicochemical methods to functionalize, purify, and characterize surface-decorated lipid-based nanocarriers
L Guyon, AC Groo, A Malzert-Freon - Molecular Pharmaceutics, 2020 - ACS Publications
Surface functionalization of lipid-based nanocarriers (LBNCs) with targeting ligands has
attracted huge interest in the field of nanomedicines for their ability to overcome some …
attracted huge interest in the field of nanomedicines for their ability to overcome some …
Are all poorly soluble drugs dissolved in deep eutectic solvents true solutions?
J Zhu, Y Wei, J Zhang, S Qian, Y Gao… - Journal of Colloid and …, 2023 - Elsevier
Hypothesis: The ability of deep eutectic solvents (DES) to enhance solubility of poorly
soluble drugs has attracted increasing attention. Researchers have shown that drugs could …
soluble drugs has attracted increasing attention. Researchers have shown that drugs could …
[HTML][HTML] Melatonin loaded nanostructured lipid carriers for the treatment of uveal melanoma
L Bonilla-Vidal, M Espina, ML García, C Cimino… - Journal of Drug Delivery …, 2024 - Elsevier
Uveal melanoma, a highly aggressive intraocular tumor and the second most common form
of ocular malignancy, currently lacks effective therapeutic options. Therefore, this study …
of ocular malignancy, currently lacks effective therapeutic options. Therefore, this study …
Binding affinity and driving forces for the interaction of calixarene-based micellar aggregates with model antibiotics in neutral aqueous solution
The search for novel surfactants or drug delivery systems able to improve the performance of
old-generation antibiotics is a topic of great interest. Self-assembling amphiphilic calix [4] …
old-generation antibiotics is a topic of great interest. Self-assembling amphiphilic calix [4] …
[HTML][HTML] Nanostructured lipid carriers co-encapsulating Apigenin and Melatonin: An innovative strategy against cancer
L Bonilla-Vidal, M Świtalska, M Espina, J Wietrzyk… - Materials & Design, 2024 - Elsevier
Cancer affects 9 million people every year constituting one of the main causes of death.
However, current treatments are frequently associated with adverse effects and can exhibit …
However, current treatments are frequently associated with adverse effects and can exhibit …
[HTML][HTML] Combination of Apigenin and Melatonin with nanostructured lipid carriers as anti-inflammatory ocular treatment
L Bonilla-Vidal, M Espina, ML García, L Baldomà… - International Journal of …, 2024 - Elsevier
Ocular inflammation is a complex pathology with limited treatment options. While traditional
therapies have side effects, novel approaches, such as natural compounds like Apigenin …
therapies have side effects, novel approaches, such as natural compounds like Apigenin …
[HTML][HTML] Novel nanostructured lipid carriers loading Apigenin for anterior segment ocular pathologies
L Bonilla-Vidal, M Espina, ML García, L Baldomà… - International journal of …, 2024 - Elsevier
Dry eye disease (DED) is a chronic multifactorial disorder of the ocular surface caused by
tear film dysfunction and constitutes one of the most common ocular conditions worldwide …
tear film dysfunction and constitutes one of the most common ocular conditions worldwide …