There is a growing consensus that the antioxidant and anti-inflammatory properties of
melatonin are of great importance in preserving the body functions and homeostasis, with …

A prominent health issue nowadays is the COVID-19 pandemic, which poses acute risks to
human health. However, the long-term health consequences are largely unknown and …

The development of the endometrium is a cyclic event tightly regulated by hormones and
growth factors to coordinate the menstrual cycle while promoting a suitable …

Preterm birth is associated with a high risk of morbidity and mortality including brain damage
and cerebral palsy. The development of brain injury in the preterm infant may be influenced …

Preterm birth (PTB) is defined as delivery before 37 weeks of gestation. Globally, 15 million
infants are born prematurely, putting these children at an increased risk of mortality and …

Human pregnancy is a sequence of events finely tuned by several molecular interactions
that come with a new birth. The precise interlocking of these events affecting the …

Reactive oxygen species have a crucial role in the pathogenesis of perinatal diseases.
Exposure to inflammation, infections, or high oxygen concentrations is frequent in preterm …

Melatonin (N-acetyl-5-methoxytryptamine) is an indolamine hormone with many
physiological and biological roles. Melatonin is an antioxidant, anti-inflammatory, free …

The circadian clock coordinates physiology, metabolism, and behavior with the 24-h cycles
of environmental light. Fundamental mechanisms of how the circadian clock regulates organ …

During pregnancy, cycles of hypoxia and oxidative stress play a key role in the proper
development of the fetus. Hypoxia during the first weeks is crucial for placental development …