Cardiac resynchronisation therapy (CRT) has an established role in the management of
patients with heart failure, reduced left ventricular ejection fraction (LVEF< 35%) and …

Background Although cardiac resynchronization therapy (CRT) is effective for some patients
with heart failure and a reduced left ventricular ejection fraction (HFrEF), evidence gaps …

Background Although the “obesity paradox” is comprehensively elucidated in heart failure
(HF) with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF) …

Alterations in connexins and specifically in 43 isoform (Cx43) in the heart have been
associated with a high incidence of arrhythmogenesis and sudden death in several cardiac …

Background Pronounced echocardiographically measured mechanical dyssynchrony is a
positive predictor of response to cardiac resynchronization therapy (CRT), whereas right …

Background In patients with left ventricular (LV) dysssynchrony, contraction that doesn't fall
into ejection period (LVEj) results in a waste of energy due to inappropriate contraction …

The role of electromechanical dyssynchrony in heart failure gained prominence in literature
with the results of trials of cardiac resynchronization therapy (CRT). CRT has shown to …

Heart failure (HF) is a complex medical condition characterized by both electrical and
mechanical dyssynchrony. Both dyssynchrony mechanisms are intricately linked together …

The term, dyssynchrony, refers to discoordination in contraction of myocardial wall
segments. Myocardial dyssynchrony has been described in a series of different pathologies …

Cardiac resynchronization therapy (CRT) is an established therapeutic option for the subset
of patients with heart failure (HF), reduced ejection fraction (EF), and dyssynchrony …