Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

Heart failure (HF) is a complex clinical syndrome characterized by the activation of at least
several neurohumoral pathways that have a common role in maintaining cardiac output and …

The patient is a 63-year-old man with a history of wellcontrolled hypertension who is
diagnosed with diffuse large B-cell lymphoma and treated with a doxorubicincontaining …

Nitric oxide (NO) is generated endogenously by NO synthases to regulate a number of
physiological processes including cardiovascular and metabolic functions. A decrease in the …

Although its clinical use in Europe dates almost 10 years, nebivolol is a β-blocker that has
been only recently introduced in the US market. Like carvedilol, nebivolol belongs to the …

Among all physiologic functions of nitric oxide (NO) known so far, NO-dependent regulation
of vascular tone is one of the most important. Under physiological conditions vascular NO is …

Background—β1-2-adrenergic receptors (AR) are key regulators of cardiac contractility and
remodeling in response to catecholamines. β3-AR expression is enhanced in diseased …

The unique conditions of space harbor considerable challenges for astronauts to overcome.
Namely, the ionizing content of space radiation and the effects of microgravity have been …

The sympathetic nervous system is central for the neurohumoral regulation of the
cardiovascular system and is largely involved in many cardiovascular diseases affecting …

Within the family of endogenous gasotransmitters, nitric oxide (NO) is the smallest gaseous
intercellular messenger involved in the modulation of several processes, such as blood flow …