Histological methods to assess skeletal muscle degeneration and regeneration in Duchenne muscular dystrophy
N Dubuisson, R Versele, C Planchon… - International journal of …, 2022 - mdpi.com
Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of
function of the protein dystrophin. This protein contributes to the stabilisation of striated cells …
function of the protein dystrophin. This protein contributes to the stabilisation of striated cells …
Computational pathology for musculoskeletal conditions using machine learning: advances, trends, and challenges
Histopathology is widely used to analyze clinical biopsy specimens and tissues from pre-
clinical models of a variety of musculoskeletal conditions. Histological assessment relies on …
clinical models of a variety of musculoskeletal conditions. Histological assessment relies on …
Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle
Skeletal muscle has the remarkable ability to regenerate. However, with age and disease
muscle strength and function decline. Myofiber size, which is affected by injury and disease …
muscle strength and function decline. Myofiber size, which is affected by injury and disease …
Myosoft: An automated muscle histology analysis tool using machine learning algorithm utilizing FIJI/ImageJ software
Skeletal muscle is comprised of a heterogeneous population of muscle fibers which can be
classified by their metabolic and contractile properties (fiber “types”). Fiber type is a primary …
classified by their metabolic and contractile properties (fiber “types”). Fiber type is a primary …
Effects of lycopene on skeletal muscle-fiber type and high-fat diet-induced oxidative stress
S Liu, D Yang, L Yu, Z Aluo, Z Zhang, Y Qi, Y Li… - The Journal of …, 2021 - Elsevier
Increasing studies report that many natural products can participate in formation of muscle
fibers. This study aimed to investigate the effect of lycopene on skeletal muscle-fiber type in …
fibers. This study aimed to investigate the effect of lycopene on skeletal muscle-fiber type in …
Bioengineered 3D skeletal muscle model reveals complement 4b as a cell‐autonomous mechanism of impaired regeneration with aging
A mechanistic understanding of cell‐autonomous skeletal muscle changes after injury can
lead to novel interventions to improve functional recovery in an aged population. However …
lead to novel interventions to improve functional recovery in an aged population. However …
MyoSight—semi-automated image analysis of skeletal muscle cross sections
LW Babcock, AD Hanna, NH Agha, SL Hamilton - Skeletal muscle, 2020 - Springer
Background Manual analysis of cross-sectional area, fiber-type distribution, and total and
centralized nuclei in skeletal muscle cross sections is tedious and time consuming …
centralized nuclei in skeletal muscle cross sections is tedious and time consuming …
Effects of eccentric, concentric and eccentric/concentric training on muscle function and mass, functional performance, cardiometabolic health, quality of life and …
Background Chronic obstructive pulmonary disease (COPD) is the third cause of death
worldwide. COPD is characterised by dyspnoea, limited exercise tolerance, and muscle …
worldwide. COPD is characterised by dyspnoea, limited exercise tolerance, and muscle …
General image fiber tool: A concept for automated evaluation of fiber diameters in SEM images
A Götz, V Senz, W Schmidt, J Huling, N Grabow… - Measurement, 2021 - Elsevier
Fiber imaging is becoming increasingly important in various fields. The current standard
method of quality assurance is the manual quantification of fiber diameters in Scanning …
method of quality assurance is the manual quantification of fiber diameters in Scanning …
Pathological and comprehensive genetic investigation of autopsy cases of idiopathic bradyarrhythmia
Y Hata, S Ichimata, K Hirono, Y Yamaguchi… - Circulation …, 2022 - jstage.jst.go.jp
Background: Idiopathic bradyarrhythmia is considered to be due to pathological
degeneration of the cardiac conduction system (CCS) during aging. There appears to have …
degeneration of the cardiac conduction system (CCS) during aging. There appears to have …