Dysbiosis of gut microbiota and microbial metabolites in Parkinson's Disease
MF Sun, YQ Shen - Ageing research reviews, 2018 - Elsevier
Gut microbial dysbiosis and alteration of microbial metabolites in Parkinson's disease (PD)
have been increasingly reported. Dysbiosis in the composition and abundance of gut …
have been increasingly reported. Dysbiosis in the composition and abundance of gut …
The microbiome: stress, health and disease
Bacterial colonisation of the gut plays a major role in postnatal development and maturation
of key systems that have the capacity to influence central nervous system (CNS) …
of key systems that have the capacity to influence central nervous system (CNS) …
The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
Bacterial colonisation of the intestine has a major role in the post-natal development and
maturation of the immune and endocrine systems. These processes are key factors …
maturation of the immune and endocrine systems. These processes are key factors …
Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice
The autoimmune disease systemic lupus erythematosus (SLE) is characterized by the
production of pathogenic autoantibodies. It has been postulated that gut microbial dysbiosis …
production of pathogenic autoantibodies. It has been postulated that gut microbial dysbiosis …
The impact of microbiota on brain and behavior: mechanisms & therapeutic potential
There is increasing evidence that host-microbe interactions play a key role in maintaining
homeostasis. Alterations in gut microbial composition is associated with marked changes in …
homeostasis. Alterations in gut microbial composition is associated with marked changes in …
Microorganisms, tryptophan metabolism, and kynurenine pathway: a complex interconnected loop influencing human health status
M Dehhaghi… - International journal …, 2019 - journals.sagepub.com
The kynurenine pathway is important in cellular energy generation and limiting cellular
ageing as it degrades about 90% of dietary tryptophan into the essential co-factor NAD+ …
ageing as it degrades about 90% of dietary tryptophan into the essential co-factor NAD+ …
[HTML][HTML] Indolepropionic acid, a metabolite of the microbiome, has cytostatic properties in breast cancer by activating AHR and PXR receptors and inducing oxidative …
Oncobiotic transformation of the gut microbiome may contribute to the risk of breast cancer.
Recent studies have provided evidence that the microbiome secretes cytostatic metabolites …
Recent studies have provided evidence that the microbiome secretes cytostatic metabolites …
[HTML][HTML] Tryptophan metabolism is a physiological integrator regulating circadian rhythms
Objective The circadian clock aligns physiology with the 24-hour rotation of Earth. Light and
food are the main environmental cues (zeitgebers) regulating circadian rhythms in …
food are the main environmental cues (zeitgebers) regulating circadian rhythms in …
[HTML][HTML] The role of the microbiome in ovarian cancer: mechanistic insights into oncobiosis and to bacterial metabolite signaling
Ovarian cancer is characterized by dysbiosis, referred to as oncobiosis in neoplastic
diseases. In ovarian cancer, oncobiosis was identified in numerous compartments, including …
diseases. In ovarian cancer, oncobiosis was identified in numerous compartments, including …
Persistent central inflammation and region specific cellular activation accompany depression-and anxiety-like behaviours during the resolution phase of experimental …
Depression and anxiety-related psychological symptoms are increasingly recognised as
important co-morbidities in patients with inflammatory bowel disease (IBD). Dextran sulfate …
important co-morbidities in patients with inflammatory bowel disease (IBD). Dextran sulfate …