Chromosomal instability: a key driver in glioma pathogenesis and progression
Chromosomal instability (CIN) is a pivotal factor in gliomas, contributing to their complexity,
progression, and therapeutic challenges. CIN, characterized by frequent genomic alterations …
progression, and therapeutic challenges. CIN, characterized by frequent genomic alterations …
Chimeric antigen receptor T-cell therapy in patients with malignant glioma—From neuroimmunology to clinical trial design considerations
M Gallus, JS Young, S Cook Quackenbush… - Neuro …, 2024 - academic.oup.com
Clinical trials evaluating chimeric antigen receptor (CAR) T-cell therapy in patients with
malignant gliomas have shown some early promise in pediatric and adult patients. However …
malignant gliomas have shown some early promise in pediatric and adult patients. However …
Navigating the mutation maze: An oncogenic driver's guide to macrophage reprogramming
The mechanisms by which oncogenic mutations and anatomical locations work together to
influence the immune environment within tumors are not well understood. In this issue of …
influence the immune environment within tumors are not well understood. In this issue of …