Molecular pathogenesis of malignant mesothelioma
Y Sekido - Carcinogenesis, 2013 - academic.oup.com
Malignant mesothelioma (MM) is an aggressive tumor arising primarily from the pleural or
peritoneal cavities. It develops by asbestos exposure after a long latency, which is …
peritoneal cavities. It develops by asbestos exposure after a long latency, which is …
Genotoxicity and carcinogenicity risk of carbon nanotubes
S Toyokuni - Advanced Drug Delivery Reviews, 2013 - Elsevier
Novel materials are often commercialized without a complete assessment of the risks they
pose to human health because such assessments are costly and time-consuming; …
pose to human health because such assessments are costly and time-consuming; …
Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis
H Nagai, Y Okazaki, SH Chew… - Proceedings of the …, 2011 - National Acad Sciences
Multiwalled carbon nanotubes (MWCNTs) have the potential for widespread applications in
engineering and materials science. However, because of their needle-like shape and high …
engineering and materials science. However, because of their needle-like shape and high …
Malignant mesothelioma as an oxidative stress-induced cancer: An update
SH Chew, S Toyokuni - Free Radical Biology and Medicine, 2015 - Elsevier
Malignant mesothelioma (MM) is a relatively rare cancer that occurs almost exclusively
following respiratory exposure to asbestos in humans. Its pathogenesis is closely associated …
following respiratory exposure to asbestos in humans. Its pathogenesis is closely associated …
Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer
S Akatsuka, Y Yamashita, H Ohara, YT Liu, M Izumiya… - 2012 - journals.plos.org
Iron overload has been associated with carcinogenesis in humans. Intraperitoneal
administration of ferric nitrilotriacetate initiates a Fenton reaction in renal proximal tubules of …
administration of ferric nitrilotriacetate initiates a Fenton reaction in renal proximal tubules of …
Iron overload signature in chrysotile‐induced malignant mesothelioma
L Jiang, S Akatsuka, H Nagai, SH Chew… - The Journal of …, 2012 - Wiley Online Library
Exposure to asbestos is a risk for malignant mesothelioma (MM) in humans. Among the
commercially used types of asbestos (chrysotile, crocidolite, and amosite), the …
commercially used types of asbestos (chrysotile, crocidolite, and amosite), the …
[HTML][HTML] Epidemiological and nonclinical studies investigating effects of iron in carcinogenesis—a critical review
The efficacy and tolerability of intravenous (iv) iron in managing cancer-related anemia and
iron deficiency has been clinically evaluated and reviewed recently. However, long-term …
iron deficiency has been clinically evaluated and reviewed recently. However, long-term …
Recent progress and perspectives on the mechanisms underlying Asbestos toxicity
A Kuroda - Genes and Environment, 2021 - Springer
Most cases of mesothelioma are known to result from exposure to asbestos fibers in the
environment or occupational ambient air. The following questions regarding asbestos …
environment or occupational ambient air. The following questions regarding asbestos …
Differences and similarities between carbon nanotubes and asbestos fibers during mesothelial carcinogenesis: shedding light on fiber entry mechanism
H Nagai, S Toyokuni - Cancer science, 2012 - Wiley Online Library
The emergence of nanotechnology represents an important milestone, as it opens the way
to a broad spectrum of applications for nanomaterials in the fields of engineering, industry …
to a broad spectrum of applications for nanomaterials in the fields of engineering, industry …
Asbestos conceives Fe (II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium
F Ito, I Yanatori, Y Maeda, K Nimura, S Ito, T Hirayama… - Redox Biology, 2020 - Elsevier
Asbestos is still a social burden worldwide as a carcinogen causing malignant
mesothelioma. Whereas recent studies suggest that local iron reduction is a preventive …
mesothelioma. Whereas recent studies suggest that local iron reduction is a preventive …