The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Dopamine receptors are widely distributed within the brain where they play critical
modulator roles on motor functions, motivation and drive, as well as cognition. The …

Psychiatric disorders are now responsible for the largest proportion of the global burden of
disease, and even more challenges have been seen during the COVID-19 pandemic …

Many mental illnesses share overlapping or similar clinical symptoms, confounding the
diagnosis. It is important to systematically characterize the degree to which unique and …

Cognitive impairment is a core feature of schizophrenia and a major contributor to poor
functional outcomes. Methods for assessment of cognitive dysfunction in schizophrenia are …

Despite 50+ years of drug discovery, current antipsychotics have limited efficacy against
negative and cognitive symptoms of schizophrenia, and are ineffective—with the exception …

One important challenge in psychiatric research is to translate findings from brain imaging
research studies that identified brain alterations in patient groups into an accurate diagnosis …

Schizophrenia (SCZ) is a debilitating neuropsychiatric disorder with high heritability and
complex inheritance. In the past decade, successful identification of numerous susceptibility …

Introduction Growing demand for mental health services, coupled with funding and resource
limitations, creates an opportunity for novel technological solutions including artificial …

Schizophrenia (SCZ) is a highly heterogeneous disorder with diverse clinical manifestations
and macro-and microscale biological variations, usually observed at dissociable levels …