Adverse drug reactions and drug–drug interactions with over-the-counter NSAIDs

N Moore, C Pollack, P Butkerait - Therapeutics and clinical risk …, 2015 - Taylor & Francis
Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen have a long history of safe
and effective use as both prescription and over-the-counter (OTC) analgesics/antipyretics …

Synergy research: approaching a new generation of phytopharmaceuticals

H Wagner, G Ulrich-Merzenich - Phytomedicine, 2009 - Elsevier
The longstanding, successful use of herbal drug combinations in traditional medicine makes
it necessary to find a rationale for the pharmacological and therapeutic superiority of many of …

Herbal medicines and perioperative care

MK Ang-Lee, J Moss, CS Yuan - Jama, 2001 - jamanetwork.com
ContextWidespread use of herbal medications among the presurgical population may have
a negative impact on perioperative patient care. ObjectivesTo review the literature on …

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

LB Moore, B Goodwin, SA Jones… - Proceedings of the …, 2000 - National Acad Sciences
St. John's wort (Hypericum perforatum) is an herbal remedy used widely for the treatment of
depression. Recent clinical studies demonstrate that hypericum extracts increase the …

Interactions between herbal medicines and prescribed drugs: a systematic review

AA Izzo, E Ernst - Drugs, 2001 - Springer
Despite the widespread use of herbal medicines, documented herb-drug interactions are
sparse. We have reviewed the literature to determine the possible interactions between the …

Clinical relevance of St. John's wort drug interactions revisited

S Nicolussi, J Drewe, V Butterweck… - British journal of …, 2020 - Wiley Online Library
The first clinically relevant reports of preparations of St. John's wort (SJW), a herbal medicine
with anti‐depressant effects, interacting with other drugs, altering their bioavailability and …

Hypericin in cancer treatment: more light on the way

P Agostinis, A Vantieghem, W Merlevede… - The international journal …, 2002 - Elsevier
Photodynamic therapy (PDT) has been described as a promising new modality for the
treatment of cancer. PDT involves the combination of a photosensitizing agent …

Polycyclic polyprenylated acylphloroglucinols

R Ciochina, RB Grossman - Chemical reviews, 2006 - ACS Publications
In recent years, the antidepressant activity of Hypericum perforatum, commonly known as St.
John's wort, has attracted much attention from both scientists1-4 and the wider public. 5 …

Mechanism of action of St John's wort in depression: what is known?

V Butterweck - CNS drugs, 2003 - Springer
Extracts of Hypericum perforatum L.(St John's wort) are now successfully competing for
status as a standard antidepressant therapy. Because of this, great effort has been devoted …

St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature

JM Greeson, B Sanford, DA Monti - Psychopharmacology, 2001 - Springer
Rationale: St. John's wort (Hypericum perforatum) has recently gained popularity as an
alternative treatment for mild to moderate depression. Given the current widespread use of …