Folic acid and the prevention of birth defects: 30 years of opportunity and controversies

KS Crider, YP Qi, LF Yeung, CT Mai… - Annual review of …, 2022 - annualreviews.org
For three decades, the US Public Health Service has recommended that all persons capable
of becoming pregnant consume 400 μg/day of folic acid (FA) to prevent neural tube defects …

Folic acid food fortification—its history, effect, concerns, and future directions

KS Crider, LB Bailey, RJ Berry - Nutrients, 2011 - mdpi.com
Periconceptional intake of folic acid is known to reduce a woman's risk of having an infant
affected by a neural tube birth defect (NTD). National programs to mandate fortification of …

The epidemiology of global micronutrient deficiencies

RL Bailey, KP West Jr, RE Black - Annals of nutrition and metabolism, 2015 - karger.com
Micronutrients are essential to sustain life and for optimal physiological function.
Widespread global micronutrient deficiencies (MNDs) exist, with pregnant women and their …

[PDF][PDF] Born too soon: the global action report on preterm birth

World Health Organization - 2012 - apps.who.int
Born Too Soon: The Global Action Report on Preterm Birth features the first-ever estimates
of preterm birth rates by country and is authored by a broad group of 45 international multi …

Pre-conception folic acid and multivitamin supplementation for the primary and secondary prevention of neural tube defects and other folic acid-sensitive congenital …

RD Wilson, F Audibert, JA Brock, J Carroll… - Journal of Obstetrics and …, 2015 - Elsevier
Objective To provide updated information on the pre-and post-conception use of oral folic
acid with or without a multivitamin/micronutrient supplement for the prevention of neural tube …

Preconception care: nutritional risks and interventions

SV Dean, ZS Lassi, AM Imam, ZA Bhutta - Reproductive health, 2014 - Springer
Introduction There is increasingly a double burden of under-nutrition and obesity in women
of reproductive age. Preconception underweight or overweight, short stature and …

Neural tube defects, folic acid and methylation

A Imbard, JF Benoist, HJ Blom - International journal of environmental …, 2013 - mdpi.com
Neural tube defects (NTDs) are common complex congenital malformations resulting from
failure of the neural tube closure during embryogenesis. It is established that folic acid …

Facts and recommendations about total homocysteine determinations: an expert opinion

H Refsum, AD Smith, PM Ueland, E Nexo… - Clinical …, 2004 - academic.oup.com
Background: Measurement of plasma total homocysteine has become common as new
methods have been introduced. A wide range of disorders are associated with increased …

Folic acid to reduce neonatal mortality from neural tube disorders

H Blencowe, S Cousens, B Modell… - International journal of …, 2010 - academic.oup.com
Abstract Background Neural tube defects (NTDs) remain an important, preventable cause of
mortality and morbidity. High-income countries have reported large reductions in NTDs …

[HTML][HTML] Reduction in neural-tube defects after folic acid fortification in Canada

P De Wals, F Tairou, MI Van Allen, SH Uh… - … England Journal of …, 2007 - Mass Medical Soc
Background In 1998, folic acid fortification of a large variety of cereal products became
mandatory in Canada, a country where the prevalence of neural-tube defects was …