Metabolomics for investigating physiological and pathophysiological processes
DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies
MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …
developments in molecular analysis, which include important advances in instrumental …
Analysis of the human adult urinary metabolome variations with age, body mass index, and gender by implementing a comprehensive workflow for univariate and …
EA Thévenot, A Roux, Y Xu, E Ezan… - Journal of proteome …, 2015 - ACS Publications
Urine metabolomics is widely used for biomarker research in the fields of medicine and
toxicology. As a consequence, characterization of the variations of the urine metabolome …
toxicology. As a consequence, characterization of the variations of the urine metabolome …
Global metabolic profiling of animal and human tissues via UPLC-MS
Obtaining comprehensive, untargeted metabolic profiles for complex solid samples, eg,
animal tissues, requires sample preparation and access to information-rich analytical …
animal tissues, requires sample preparation and access to information-rich analytical …
Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database
Untargeted metabolomics provides a comprehensive platform for identifying metabolites
whose levels are altered between two or more populations. By using liquid chromatography …
whose levels are altered between two or more populations. By using liquid chromatography …
The human gut microbiome and body metabolism: implications for obesity and diabetes
S Devaraj, P Hemarajata, J Versalovic - Clinical chemistry, 2013 - academic.oup.com
BACKGROUND Obesity, metabolic syndrome, and type 2 diabetes are major public health
challenges. Recently, interest has surged regarding the possible role of the intestinal …
challenges. Recently, interest has surged regarding the possible role of the intestinal …
New advances in separation science for metabolomics: resolving chemical diversity in a post-genomic era
NL Kuehnbaum, P Britz-McKibbin - Chemical reviews, 2013 - ACS Publications
Metabolomics offers a revolutionary framework for phenotyping individuals at a molecular
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …
Salivary metabolomics: from diagnostic biomarker discovery to investigating biological function
A Gardner, G Carpenter, PW So - Metabolites, 2020 - mdpi.com
Metabolomic profiling of biofluids, eg, urine, plasma, has generated vast and ever-
increasing amounts of knowledge over the last few decades. Paradoxically, metabolomic …
increasing amounts of knowledge over the last few decades. Paradoxically, metabolomic …
Metabolic fingerprinting on synthetic alloys for medulloblastoma diagnosis and radiotherapy evaluation
J Cao, X Shi, DD Gurav, L Huang, H Su, K Li… - Advanced …, 2020 - Wiley Online Library
Diagnostics is the key in screening and treatment of cancer. As an emerging tool in precision
medicine, metabolic analysis detects end products of pathways, and thus is more distal than …
medicine, metabolic analysis detects end products of pathways, and thus is more distal than …
Cancer metabolomic markers in urine: evidence, techniques and recommendations
SS Dinges, A Hohm, LA Vandergrift, J Nowak… - Nature reviews …, 2019 - nature.com
Urinary tests have been used as noninvasive, cost-effective tools for screening, diagnosis
and monitoring of diseases since ancient times. As we progress through the 21st century …
and monitoring of diseases since ancient times. As we progress through the 21st century …