Ionizing radiation biomarkers in epidemiological studies–an update

J Hall, PA Jeggo, C West, M Gomolka… - … Research/Reviews in …, 2017 - Elsevier
Recent epidemiology studies highlighted the detrimental health effects of exposure to low
dose and low dose rate ionizing radiation (IR): nuclear industry workers studies have shown …

Secretory microRNAs as biomarkers of cancer

K Kai, RL Dittmar, S Sen - Seminars in cell & developmental biology, 2018 - Elsevier
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression
predominantly by inhibiting transcription and/or promoting degradation of target mRNAs also …

Stability of circulating blood-based microRNAs–pre-analytic methodological considerations

C Glinge, S Clauss, K Boddum, R Jabbari, J Jabbari… - PloS one, 2017 - journals.plos.org
Background and aim The potential of microRNAs (miRNA) as non-invasive diagnostic,
prognostic, and predictive biomarkers, as well as therapeutic targets, has recently been …

Challenges in using circulating micro-RNAs as biomarkers for cardiovascular diseases

K Felekkis, C Papaneophytou - International Journal of Molecular …, 2020 - mdpi.com
Micro-RNAs (miRNAs) play a pivotal role in the development and physiology of the
cardiovascular system while they have been associated with multiple cardiovascular …

Understanding preanalytical variables and their effects on clinical biomarkers of oncology and immunotherapy

L Agrawal, KB Engel, SR Greytak, HM Moore - Seminars in cancer biology, 2018 - Elsevier
Identifying a suitable course of immunotherapy treatment for a given patient as well as
monitoring treatment response is heavily reliant on biomarkers detected and quantified in …

[HTML][HTML] Variability in, variability out: best practice recommendations to standardize pre-analytical variables in the detection of circulating and tissue microRNAs

J Khan, JA Lieberman, CM Lockwood - Clinical Chemistry and …, 2017 - degruyter.com
microRNAs (miRNAs) hold promise as biomarkers for a variety of disease processes and for
determining cell differentiation. These short RNA species are robust, survive harsh treatment …

The growing impact of micro/nanomaterial‐based systems in precision oncology: Translating “multiomics” technologies

J Li, A Wuethrich, S Dey, RE Lane… - Advanced Functional …, 2020 - Wiley Online Library
The field of precision oncology is rapidly progressing toward integrated “multiomics”
analysis of multiple molecular species (such as DNA, RNA, or proteins) to provide a more …

[HTML][HTML] Whole blood microRNAs capture systemic reprogramming and have diagnostic potential in patients with biliary tract cancer

D Høgdall, CJ O'Rourke, FO Larsen, S Zarforoushan… - Journal of …, 2022 - Elsevier
Background & Aims Late diagnosis is a critical factor undermining clinical management of
patients with biliary tract cancer (BTC). While biliary tumours display extensive inter-patient …

Function and regulation of microRNAs and their potential as biomarkers in paediatric liver disease

DA Calvopina, MA Coleman, PJ Lewindon… - International journal of …, 2016 - mdpi.com
MicroRNAs (miRNAs) are short non-coding RNAs involved in biological and pathological
processes of every cell type, including liver cells. Transcribed from specific genes, miRNA …

Storage Stability of Blood Samples for miRNAs in Glycosylated Extracellular Vesicles

C Ma, R Ding, K Hao, W Du, L Xu, Q Gao, C Yu - Molecules, 2023 - mdpi.com
Extracellular vesicle (EV) miRNAs are promising biomarkers for clinical diagnosis. However,
their stability is a crucial concern affecting reliability and accuracy. Factors such as sample …