[HTML][HTML] Multiple myeloma with t (11; 14): unique biology and evolving landscape

S Bal, SK Kumar, R Fonseca, F Gay… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Multiple myeloma is characterized by heterogeneity in clinical presentation, response to
treatment, and importantly, patient outcomes. The translocation of chromosomes 11 and 14 [t …

Exploring the current molecular landscape and management of multiple myeloma patients with the t (11; 14) translocation

MD Diamantidis, S Papadaki, E Hatjiharissi - Frontiers in Oncology, 2022 - frontiersin.org
Multiple myeloma (MM) is a genetically complex disease. The key myeloma-initiating
genetic events are hyperdiploidy and translocations involving the immunoglobulin heavy …

Multiple myeloma with t (11; 14): impact of novel agents on outcome

B Puertas, V González-Calle… - Blood Cancer …, 2023 - nature.com
Multiple myeloma (MM) patients with t (11; 14) present unique biological features and their
prognosis is not well established. We report a retrospective study of 591 MM patients, 17.3 …

What multiple myeloma with t (11; 14) should be classified into in novel agent era: standard or intermediate risk?

W Gao, J Du, J Liu, H Zhou, Z Zhang, Y Jian… - Frontiers in …, 2020 - frontiersin.org
Objective To investigate the prognostic value of t (11; 14) for de novo multiple myeloma
(MM) patients in novel agent era. Methods A total of 455 patients with fluorescence in situ …

Precision medicine for multiple myeloma: The case for translocation (11; 14)

AH Bazarbachi, H Avet-Loiseau, JL Harousseau… - Cancer Treatment …, 2024 - Elsevier
Abstract The t (11; 14) translocation is among the most prevalent cytogenetic abnormalities
in multiple myeloma (MM), distinguished by its unique features and biology that have been …

Upfront stem cell transplantation for newly diagnosed multiple myeloma with del (17p) and t (4; 14): a study from the CMWP-EBMT

N Gagelmann, DJ Eikema, LC De Wreede… - Bone marrow …, 2021 - nature.com
We analyzed newly diagnosed multiple myeloma patients with del (17p) and/or t (4; 14)
undergoing either upfront single autologous (auto), tandem autologous (auto-auto) or …

Is t (11; 14)(q13; q32) good or bad for newly diagnosed multiple myeloma?

Y Liu, L Gao, Y Lai, L Wen, W Duan, F Wang… - Chinese Medical …, 2023 - mednexus.org
Cytogenetic aberrations (CAs) are vital markers for risk stratification of multiple myeloma
(MM). The prognostic significance of the aberration, t (11; 14)(q13; q32), in MM has …

The influence of high-efficiency particulate air filtration on mortality among multiple myeloma patients receiving autologous stem cell transplantation

CK Tsai, CM Yeh, YC Hong, PM Chen, JH Liu… - Scientific reports, 2021 - nature.com
Autologous stem cell transplantation (ASCT) continues to be the standard treatment for
transplant-eligible multiple myeloma (MM) patients. A portion of MM patients received ASCT …

Multiple myeloma with t (11; 14): impact of novel agents on outcome

B Puertas Martínez, V González-Calle… - 2023 - digital.csic.es
Multiple myeloma (MM) patients with t (11; 14) present unique biological features and their
prognosis is not well established. We report a retrospective study of 591 MM patients, 17.3 …

Multiple myeloma and t (11; 14): prognostic significance and impact of novel agents on response and survival.

B Puertas, V González-Calle, E Sobejano, F Escalante… - 2022 - researchsquare.com
Multiple myeloma (MM) patients with t (11; 14) present unique biological features and their
prognosis is not well established. We report a retrospective study of 591 MM patients, 17.6 …