Diseases of the central nervous system (CNS) are challenging to treat, mainly due to the
blood-brain barrier (BBB), which restricts drugs in circulation from entering target regions in …

Extracellular vesicles (EVs) are widely recognized for their potential as drug delivery
systems. EVs are membranous nanoparticles shed from cells. Among their natural features …

Extracellular vesicles (EVs) are a population of small vesicles secreted by essentially all cell
types, containing a wide variety of biological macromolecules. Due to their intrinsic …

Background Glioblastoma (GBM) has poor prognosis due to ineffective agents and poor
delivery methods. MicroRNAs (miRs) have been explored as novel therapeutics for GBM …

Suicide gene therapy is a relatively novel form of cancer therapy in which a gene coding for
enzymes or protein toxins is delivered through targeting systems such as vesicles …

In the central nervous system (CNS), the crosstalk between neural cells is mediated by
extracellular mechanisms, including brain-derived extracellular vesicles (bdEVs). To study …

Sepsis is a syndromic response to infection and is frequently a final common pathway to
death from many infectious diseases worldwide. The complexity and high heterogeneity of …

Gene editing technologies have the potential to correct genetic disorders by modifying,
inserting, or deleting specific DNA sequences or genes, paving the way for a new class of …

The successful application of messenger RNA vaccines in the market has demonstrated the
potential of gene therapy in treating various diseases, including infectious diseases …

Messenger ribonucleic acid (RNA) vaccines are mainly used as SARS-CoV-2 vaccines.
Despite several issues concerning storage, stability, effective period, and side effects, viral …