Diffuse midline glioma (DMG), formerly called diffuse intrinsic pontine glioma (DIPG), is a
high-grade malignant pediatric brain tumor with a near-zero survival rate. To date, only …

Until recently, cells were thought to be integral and discrete components of tissues, and their
state was determined by cell differentiation. However, under some conditions, stem cells or …

Multipotent stem cells are thought to be responsible for the generation of new neurons in the
adult brain. Neurogenesis also occurs in an accessible part of the nervous system, the …

The ability to fuse cells is shared by many viruses, including common human pathogens and
several endogenous viruses. Here we will discuss how cell fusion can link viruses to cancer …

Over the past decade, the old idea that the bone marrow contains endothelial cell precursors
has become an area of renewed interest. While some still believe that there are no …

Cell fusion likely drives tumor evolution by undermining chromosomal and DNA stability
and/or by generating phenotypic diversity; however, whether a cell fusion event can initiate …

Mammalian interspecific hybrids provide unique advantages for mechanistic studies of
speciation, gene expression regulation, and X chromosome inactivation (XCI) but are …

Diffuse intrinsic pontine glioma (DIPG), with a median survival of only 9 months, is the
leading cause of pediatric brain cancer mortality. Dearth of tumor tissue for research has …

Within the last decade there have been several severe combined immunodeficient (SCID)
pig models discovered or genetically engineered. The animals have mutations in ARTEMIS …

Evidence suggests that transplanted mesenchymal stem cells (MSCs) can aid recovery of
damaged myocardium caused by myocardial infarction. One possible mechanism for MSC …