[HTML][HTML] Dioctadecyldimethylammonium bromide, a surfactant model for the cell membrane: Importance of microscopic dynamics

VK Sharma, H Srinivasan, V García Sakai… - Structural Dynamics, 2020 - pubs.aip.org
Cationic lipid membranes have recently attracted huge attention both from a fundamental
point of view and due to their practical applications in drug delivery and gene therapy. The …

Dynamic landscape in self-assembled surfactant aggregates

VK Sharma, S Mitra, R Mukhopadhyay - Langmuir, 2019 - ACS Publications
A process in which a disordered system of pre-existing molecules generates an organized
structure through specific, local interactions among the molecules themselves is termed …

Modulation of Phase Behavior and Microscopic Dynamics in Cationic Vesicles by 1-Decyl-3-methylimidazolium Bromide

J Gupta, VK Sharma, H Srinivasan, H Bhatt, VG Sakai… - Langmuir, 2023 - ACS Publications
Synthetic cationic lipids have garnered significant attention as promising candidates for
gene/DNA transfection in therapeutic applications. The phase behavior of the vesicles …

Molecular co-localization of multiple drugs in a nanoscopic delivery vehicle for potential synergistic remediation of multi-drug resistant bacteria

A Banerjee, D Mukherjee, A Bera, R Ghosh… - Scientific reports, 2022 - nature.com
Anti-microbial resistant infection is predicted to be alarming in upcoming years. In the
present study, we proposed co-localization of two model drugs viz., rifampicin and …

Unraveling the role of monoolein in fluidity and dynamical response of a mixed cationic lipid bilayer

P Singh, VK Sharma, S Singha, V García Sakai… - Langmuir, 2019 - ACS Publications
The maintenance of cell membrane fluidity is of critical importance for various cellular
functions. At lower temperatures when membrane fluidity decreases, plants and …

Deciphering the response of asymmetry in the hydrophobic chains of novel cationic lipids towards biological function

D Mukherjee, P Singh, T Rakshit… - Physical Chemistry …, 2020 - pubs.rsc.org
Cationic liposomes, a type of non-viral vectors, often play the important biological function of
delivering nucleic acids during cell transfection. Variations in the molecular architecture of di …

Selective and fast responsive sensitized micelle for detection of fluoride level in drinking water

A Halder, S Singh, A Adhikari, P Singh… - ACS Sustainable …, 2019 - ACS Publications
Consumption of excess fluorides through drinking water and its adverse effects on human
health is of global concern. Given that people from at least 25 countries are suffering from …

Microscopic diffusion in cationic vesicles across different phases

J Gupta, VK Sharma, H Srinivasan, H Bhatt… - Physical Review …, 2022 - APS
Understanding the phase behavior and microscopic diffusion mechanism of cationic
vesicles is crucial for controlled-release kinetics in gene/DNA transfection. Here, we report …

Differential flexibility leading to crucial microelastic properties of asymmetric lipid vesicles for cellular transfection: A combined spectroscopic and atomic force …

D Mukherjee, T Rakshit, P Singh, S Mondal… - Colloids and surfaces B …, 2020 - Elsevier
The role of microscopic elasticity of nano-carriers in cellular uptake is an important aspect in
biomedical research. Herein we have used AFM nano-indentation force spectroscopy and …

[HTML][HTML] Pico-second resolved Förster resonance energy transfer (FRET) differentiates self-assembled biological macromolecules in aqueous medium

L Roy, D Mukherjee, S Singh, A Banerjee… - Chemical Physics …, 2022 - Elsevier
Major constituents of all living beings are nano-sized molecular species like lipids, proteins,
fatty acids, and nucleic acids which are constantly in communication with each other through …