Improving quality of science through better animal welfare: the NC3Rs strategy
MJ Prescott, K Lidster - Lab animal, 2017 - nature.com
Good animal welfare is linked to the quality of research data derived from laboratory
animals, their validity as models of human disease, the number of animals required to reach …
animals, their validity as models of human disease, the number of animals required to reach …
[HTML][HTML] The multifactorial role of the 3Rs in shifting the harm-benefit analysis in animal models of disease
ML Graham, MJ Prescott - European journal of pharmacology, 2015 - Elsevier
Ethics on animal use in science in Western society is based on utilitarianism, weighing the
harms and benefits to the animals involved against those of the intended human …
harms and benefits to the animals involved against those of the intended human …
Pioneering better science through the 3Rs: an introduction to the national centre for the replacement, refinement, and reduction of animals in research (NC3Rs)
N Burden, K Chapman, F Sewell… - Journal of the American …, 2015 - ingentaconnect.com
The National Centre for the Replacement, Refinement, and Reduction of Animals in
Research (NC3Rs) is an independent scientific organization that is based in the United …
Research (NC3Rs) is an independent scientific organization that is based in the United …
[HTML][HTML] Opportunities for improving animal welfare in rodent models of epilepsy and seizures
K Lidster, JG Jefferys, I Blümcke, V Crunelli… - Journal of neuroscience …, 2016 - Elsevier
Animal models of epilepsy and seizures, mostly involving mice and rats, are used to
understand the pathophysiology of the different forms of epilepsy and their comorbidities, to …
understand the pathophysiology of the different forms of epilepsy and their comorbidities, to …
Standardized automated training of rhesus monkeys for neuroscience research in their housing environment
Teaching nonhuman primates the complex cognitive behavioral tasks that are central to
cognitive neuroscience research is an essential and challenging endeavor. It is crucial for …
cognitive neuroscience research is an essential and challenging endeavor. It is crucial for …
[HTML][HTML] International primate neuroscience research regulation, public engagement and transparency opportunities
Scientific excellence is a necessity for progress in biomedical research. As research
becomes ever more international, establishing international collaborations will be key to …
becomes ever more international, establishing international collaborations will be key to …
The indispensable contribution of nonhuman primates to biomedical research
S Treue, R Lemon - Nonhuman Primate Welfare: From History, Science …, 2023 - Springer
Research in nonhuman primates is one of the cornerstones of modern biomedical research.
This approach, while quantitatively contributing only a very small component to biomedical …
This approach, while quantitatively contributing only a very small component to biomedical …
Mixed‐complexity artificial grammar learning in humans and macaque monkeys: evaluating learning strategies
Artificial grammars (AG) can be used to generate rule‐based sequences of stimuli. Some of
these can be used to investigate sequence‐processing computations in non‐human …
these can be used to investigate sequence‐processing computations in non‐human …
Assessment of stress responses in rhesus macaques (Macaca mulatta) to daily routine procedures in system neuroscience based on salivary cortisol concentrations
D Pfefferle, S Plümer, L Burchardt, S Treue, A Gail - PloS one, 2018 - journals.plos.org
Non-human primates participating in neurophysiological research are exposed to potentially
stressful experimental procedures, such as dietary control protocols, surgical implants and …
stressful experimental procedures, such as dietary control protocols, surgical implants and …