[HTML][HTML] Vitamin D deficiency in India: prevalence, causalities and interventions

A Gupta - Nutrients, 2014 - mdpi.com
Vitamin D deficiency prevails in epidemic proportions all over the Indian subcontinent, with a
prevalence of 70%–100% in the general population. In India, widely consumed food items …

How culture shaped the human genome: bringing genetics and the human sciences together

KN Laland, J Odling-Smee, S Myles - Nature Reviews Genetics, 2010 - nature.com
Researchers from diverse backgrounds are converging on the view that human evolution
has been shaped by gene–culture interactions. Theoretical biologists have used population …

Niche construction

FJ Odling-Smee, KN Laland… - The American …, 1996 - journals.uchicago.edu
Organisms, through their metabolism, their activities, and their choices, define, partly create,
and partly destroy their own niches. We refer to these phenomena as" niche construction." …

Worlds within worlds: evolution of the vertebrate gut microbiota

RE Ley, CA Lozupone, M Hamady, R Knight… - Nature Reviews …, 2008 - nature.com
In this Analysis we use published 16S ribosomal RNA gene sequences to compare the
bacterial assemblages that are associated with humans and other mammals, metazoa and …

Convergent adaptation of human lactase persistence in Africa and Europe

SA Tishkoff, FA Reed, A Ranciaro, BF Voight… - Nature …, 2007 - nature.com
A SNP in the gene encoding lactase (LCT)(C/T-13910) is associated with the ability to digest
milk as adults (lactase persistence) in Europeans, but the genetic basis of lactase …

[HTML][HTML] Genetic signatures of strong recent positive selection at the lactase gene

T Bersaglieri, PC Sabeti, N Patterson… - The American Journal of …, 2004 - cell.com
In most human populations, the ability to digest lactose contained in milk usually disappears
in childhood, but in European-derived populations, lactase activity frequently persists into …

African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping

MC Campbell, SA Tishkoff - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …

[HTML][HTML] The origins of lactase persistence in Europe

Y Itan, A Powell, MA Beaumont, J Burger… - PLoS computational …, 2009 - journals.plos.org
Lactase persistence (LP) is common among people of European ancestry, but with the
exception of some African, Middle Eastern and southern Asian groups, is rare or absent …

[HTML][HTML] Score tests for association between traits and haplotypes when linkage phase is ambiguous

DJ Schaid, CM Rowland, DE Tines… - The American Journal of …, 2002 - cell.com
A key step toward the discovery of a gene related to a trait is the finding of an association
between the trait and one or more haplotypes. Haplotype analyses can also provide critical …

Interrogating a high-density SNP map for signatures of natural selection

JM Akey, G Zhang, K Zhang, L Jin… - Genome research, 2002 - genome.cshlp.org
Identifying genomic regions that have been targets of natural selection remains one of the
most important and challenging areas of research in genetics. To this end, we report an …