Single-cell technologies for monitoring immune systems

PK Chattopadhyay, TM Gierahn, M Roederer… - Nature …, 2014 - nature.com
The complex heterogeneity of cells, and their interconnectedness with each other, are major
challenges to identifying clinically relevant measurements that reflect the state and capability …

Implication of haematophagous arthropod salivary proteins in host-vector interactions

A Fontaine, I Diouf, N Bakkali, D Missé, F Pagès… - Parasites & vectors, 2011 - Springer
The saliva of haematophagous arthropods contains an array of anti-haemostatic, anti-
inflammatory and immunomodulatory molecules that contribute to the success of the blood …

[HTML][HTML] Evaluating SARS-CoV-2 spike and nucleocapsid proteins as targets for antibody detection in severe and mild COVID-19 cases using a Luminex bead-based …

J Mariën, A Ceulemans, J Michiels, L Heyndrickx… - Journal of virological …, 2021 - Elsevier
Large-scale serosurveillance of severe acute respiratory syndrome coronavirus type 2
(SARS-CoV-2) will only be possible if serological tests are sufficiently reliable, rapid and …

Recent progress in the development of diagnostic tests for malaria

FD Krampa, Y Aniweh, GA Awandare, P Kanyong - Diagnostics, 2017 - mdpi.com
The impact of malaria on global health has continually prompted the need to develop
effective diagnostic strategies. In malaria endemic regions, routine diagnosis is hampered …

Anopheles salivary antigens as serological biomarkers of vector exposure and malaria transmission: A systematic review with multilevel modelling

EA Kearney, PA Agius, V Chaumeau, JC Cutts… - Elife, 2021 - elifesciences.org
Background: Entomological surveillance for malaria is inherently resource-intensive and
produces crude population-level measures of vector exposure which are insensitive in low …

Naturally acquired immune responses against Plasmodium falciparum sporozoites and liver infection

V Offeddu, V Thathy, K Marsh… - International journal for …, 2012 - Elsevier
Malaria is a vector-borne infectious disease caused by infection with eukaryotic pathogens
termed Plasmodium. Epidemiological hallmarks of Plasmodium falciparum malaria are …

Peptide biomarkers for the diagnosis of dengue infection

F Falconi-Agapito, K Kerkhof, X Merino… - Frontiers in …, 2022 - frontiersin.org
In a world with an increasing population at risk of exposure to arthropod-borne flaviviruses,
access to timely and accurate diagnostic tests would impact profoundly on the management …

Serological markers to measure recent changes in malaria at population level in Cambodia

K Kerkhof, V Sluydts, L Willen, S Kim, L Canier, S Heng… - Malaria journal, 2016 - Springer
Background Serological markers for exposure to different Plasmodium species have
recently been used in multiplex immunoassays based on the Luminex technology. However …

Acquisition and longevity of antibodies to Plasmodium vivax preerythrocytic antigens in Western Thailand

RJ Longley, A Reyes-Sandoval… - Clinical and Vaccine …, 2016 - Am Soc Microbiol
Plasmodium vivax is now the dominant Plasmodium species causing malaria in Thailand,
yet little is known about naturally acquired immune responses to this parasite in this low …

Quality control of multiplex antibody detection in samples from large-scale surveys: the example of malaria in Haiti

LL van den Hoogen, J Présumé, I Romilus… - Scientific reports, 2020 - nature.com
Measuring antimalarial antibodies can estimate transmission in a population. To compare
outputs, standardized laboratory testing is required. Here we describe the in-country …