Vedolizumab serum trough concentrations and response to dose escalation in inflammatory bowel disease

BP Vaughn, AJ Yarur, E Graziano, JP Campbell… - Journal of Clinical …, 2020 - mdpi.com
Serum vedolizumab concentrations are associated with clinical response although, it is
unknown if vedolizumab concentrations predict response to dose escalation. The aim of this …

Effect of vedolizumab dose intensification on serum drug concentrations and regain of response in inflammatory bowel disease patients with secondary loss of …

A Outtier, L Wauters, JF Rahier, P Bossuyt… - …, 2021 - Wiley Online Library
Abstract Background and Aims Dose intensification of vedolizumab (VDZ) for moderate‐to‐
severe ulcerative colitis (UC) and Crohn's disease (CD) may be effective in patients losing …

Efficacy and Safety of Vedolizumab in Patients with Inflammatory Bowel Disease in Association with Vedolizumab Drug Levels

E Hüttemann, A Muzalyova, K Gröhl, S Nagl… - Journal of Clinical …, 2023 - mdpi.com
Background: Vedolizumab (VDZ) is a well-established and important therapeutic option in
the treatment of patients with inflammatory bowel disease (IBD). However, the significance of …

Remission Is Maintained after Switch from Dose-Optimised Intravenous Treatment to Subcutaneous Treatment with Vedolizumab in Inflammatory Bowel Disease

Š Pintar, J Hanžel, D Drobne, M Koželj, T Kurent… - Medicina, 2024 - mdpi.com
Background and Objectives: The subcutaneous (SC) formulation of vedolizumab has proven
to be effective for the maintenance of remission after intravenous induction. Little is known …