Zinc coordination complexes as anticancer agents
Zinc, present in all forms of life, is an essential element for humans. It is one of the most
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …
Nanomedicines in the treatment of colon cancer: A focus on metallodrugs
P Farinha, JO Pinho, M Matias, MM Gaspar - Drug Delivery and …, 2022 - Springer
Worldwide, colon cancer (CC) represents the fourth most common type of cancer and the
fifth major cause of cancer-associated deaths. Surgical resection is considered the standard …
fifth major cause of cancer-associated deaths. Surgical resection is considered the standard …
Co (II), Ni (II), Cu (II) and Cd (II)-thiocarbonohydrazone complexes: spectroscopic, DFT, thermal, and electrical conductivity studies
New and stable coordinated compounds have been isolated in a good yield. The chelates
have been prepared by mixing Co (II), Ni (II), Cu (II), and Cd (II) metal ions with (1E)-1-((6 …
have been prepared by mixing Co (II), Ni (II), Cu (II), and Cd (II) metal ions with (1E)-1-((6 …
Nickel (II) complexes with polyhydroxybenzaldehyde and O, N, S tridentate thiosemicarbazone ligands: Synthesis, cytotoxicity, antimalarial activity, and molecular …
S Savir, JWK Liew, I Vythilingam, YAL Lim… - Journal of Molecular …, 2021 - Elsevier
A series of Schiff base metal complexes with the formulations [Ni (L1) PPh 3] Cl (1),[Ni (L2)
PPh 3] Cl (2),[Ni (L3) PPh 3](3), and [Ni (L4) PPh 3](4)(where L1= 2, 3, 4 …
PPh 3] Cl (2),[Ni (L3) PPh 3](3), and [Ni (L4) PPh 3](4)(where L1= 2, 3, 4 …
Synthesis and characterization of thiosemicarbazone metal complexes: Crystal structure, and antiproliferation activity against breast (MCF7) and lung (A549) cancers
MS Ali, FA El-Saied, MME Shakdofa, S Karnik… - Journal of Molecular …, 2023 - Elsevier
Thiosemicarbazone compound has pronounced anticancer activity, which increases by
metal ions presence. New Ni (II), Cu (II), Pd (II), and Pt (II) complexes synthesized from 2-(2 …
metal ions presence. New Ni (II), Cu (II), Pd (II), and Pt (II) complexes synthesized from 2-(2 …
Cobalt mediated N-alkylation of amines by alcohols: role of hydrogen bonding pocket
D Prabha, S Pachisia, R Gupta - Inorganic Chemistry Frontiers, 2021 - pubs.rsc.org
Cobalt complexes of amide-based pincers provide a hydrogen bonding pocket that is shown
to bind a reagent in the vicinity of a metal center. These cobalt complexes function as non …
to bind a reagent in the vicinity of a metal center. These cobalt complexes function as non …
Synthesis, structural characterization, and density functional theory calculations of the two new Zn (II) complexes as antibacterial and anticancer agents with a neutral …
A Beheshti, M Bahrani‐Pour, M Kolahi… - Applied …, 2021 - Wiley Online Library
Two new mono‐and dinuclear zinc (II) complexes with a formula of [Zn (LN) OMeCl](1) and
[Zn2 (LN)(N3) 2Cl2](2)[where LN= 1, 1, 3, 3‐tetrakis (3, 5‐dimethyl‐1‐pyrazolyl) propane)] …
[Zn2 (LN)(N3) 2Cl2](2)[where LN= 1, 1, 3, 3‐tetrakis (3, 5‐dimethyl‐1‐pyrazolyl) propane)] …
Synthesis, characterization, DNA/HSA interactions, and anticancer activity of two novel Copper (II) complexes with 4-Chloro-3-Nitrobenzoic acid ligand
ZF Zeng, QP Huang, JH Cai, GJ Zheng, QC Huang… - Molecules, 2021 - mdpi.com
The purpose of this study was to identify new metal-based anticancer drugs; to this end, we
synthesized two new copper (II) complexes, namely [Cu (ncba) 4 (phen)](1) and [Cu (ncba) 4 …
synthesized two new copper (II) complexes, namely [Cu (ncba) 4 (phen)](1) and [Cu (ncba) 4 …
The strong in vitro and vivo cytotoxicity of three new cobalt (II) complexes with 8-methoxyquinoline
YF Wang, JX Tang, ZY Mo, J Li, FP Liang… - Dalton Transactions, 2022 - pubs.rsc.org
Three new cobalt (II) complexes,[Co (MQL) 2Cl2](CoCl),[Co (MQL) 2Br2](CoBr), and [Co
(MQL) 2I2](CoI), bearing 8-methoxyquinoline (MQL) have been designed for the first time …
(MQL) 2I2](CoI), bearing 8-methoxyquinoline (MQL) have been designed for the first time …
2′-Thiophenecarboxaldehyde derived thiosemicarbazone metal complexes of copper (II), palladium (II) and zinc (II) ions: Synthesis, spectroscopic characterization …
Abstract Heterocyclic 5′-methyl-2-thiophenecarboxaldehyde-N (4)-un/substituted
thiosemicarbazones (1–3) and their metal complexes with copper (II), palladium (II) and zinc …
thiosemicarbazones (1–3) and their metal complexes with copper (II), palladium (II) and zinc …