[HTML][HTML] A weight of evidence review of the genotoxicity of titanium dioxide (TiO2)

D Kirkland, MJ Aardema, RV Battersby… - Regulatory Toxicology …, 2022 - Elsevier
Titanium dioxide is a ubiquitous white material found in a diverse range of products from
foods to sunscreens, as a pigment and thickener, amongst other uses. Titanium dioxide has …

Biology of the cell cycle inhibitor p21CDKN1A: molecular mechanisms and relevance in chemical toxicology

I Dutto, M Tillhon, O Cazzalini, LA Stivala… - Archives of toxicology, 2015 - Springer
The cell cycle inhibitor p21 CDKN1A is a protein playing multiple roles not only in the DNA
damage response, but also in many cellular processes during unperturbed cell growth. The …

Safety assessment of titanium dioxide (E171) as a food additive

EFSA Panel on Food Additives and Flavourings … - Efsa …, 2021 - Wiley Online Library
The present opinion deals with an updated safety assessment of the food additive titanium
dioxide (E 171) based on new relevant scientific evidence considered by the Panel to be …

The potential liver, brain, and embryo toxicity of titanium dioxide nanoparticles on mice

X Jia, S Wang, L Zhou, L Sun - Nanoscale research letters, 2017 - Springer
Nanoscale titanium dioxide (nano-TiO 2) has been widely used in industry and medicine.
However, the safety of nano-TiO 2 exposure remains unclear. In this study, we evaluated the …

[HTML][HTML] Genotoxicity of titanium dioxide nanoparticles

T Chen, J Yan, Y Li - Journal of food and drug analysis, 2014 - Elsevier
Abstract Titanium dioxide nanoparticles (TiO 2-NPs,< 100 nm) are increasingly being used
in pharmaceuticals and cosmetics due to the unique properties derived from their small …

Exploring the multifunctional roles of quantum dots for unlocking the future of biology and medicine

MK Ali, S Javaid, H Afzal, I Zafar, K Fayyaz… - Environmental …, 2023 - Elsevier
With recent advancements in nanomedicines and their associated research with biological
fields, their translation into clinically-applicable products is still below promises. Quantum …

Biomaterials for three-dimensional cell culture: From applications in oncology to nanotechnology

T Saydé, O El Hamoui, B Alies, K Gaudin, G Lespes… - Nanomaterials, 2021 - mdpi.com
Three-dimensional cell culture has revolutionized cellular biology research and opened the
door to novel discoveries in terms of cellular behavior and response to microenvironment …

Toxicology of nanosized titanium dioxide: an update

X Zhang, W Li, Z Yang - Archives of toxicology, 2015 - Springer
Nanosized titanium dioxide (nano-TiO 2) has tremendous potential for a host of applications,
and TiO 2 nanoparticles (NP) possess different physicochemical properties compared to …

Biodegradable plastic mulch films for sustainable specialty crop production

DG Hayes, MB Anunciado, JM DeBruyn… - Polymers for agri-food …, 2019 - Springer
Plastic mulch films are employed in the production of vegetables and other specialty crops
worldwide due to the benefits they provide, such as reduction of weeds and water loss by …

Genotoxicity assessment of nanomaterials: recommendations on best practices, assays, and methods

R Elespuru, S Pfuhler, MJ Aardema… - Toxicological …, 2018 - academic.oup.com
Nanomaterials (NMs) present unique challenges in safety evaluation. An international
working group, the Genetic Toxicology Technical Committee of the International Life …