A review on measures to rejuvenate immune system: Natural mode of protection against coronavirus infection

MA Islam, MA Haque, MA Rahman, F Hossen… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2, a novel Corona virus strain, was first detected in Wuhan, China, in December
2019. As of December 16, 2021, almost 4,822,472 people had died and over 236,132,082 …

Biochemical features and mutations of key proteins in SARS-CoV-2 and their impacts on RNA therapeutics

L Zeng, D Li, W Tong, T Shi, B Ning - Biochemical pharmacology, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic. Three viral proteins, the spike protein (S) for attachment of virus to host cells, 3 …

[HTML][HTML] Identification of bioactive molecules from Triphala (Ayurvedic herbal formulation) as potential inhibitors of SARS-CoV-2 main protease (Mpro) through …

M Rudrapal, I Celik, J Khan, MA Ansari… - Journal of King Saud …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus disease (SARS-CoV-2) induced coronavirus
disease 2019 (COVID-19) pandemic is the present worldwide health emergency. The global …

Rutin: A Potential Antiviral for Repurposing as a SARS-CoV-2 Main Protease (Mpro) Inhibitor

PK Agrawal, C Agrawal… - Natural Product …, 2021 - journals.sagepub.com
Various computational studies, including in silico ones, have identified several existing
compounds that could serve as effective inhibitors of the SARS-CoV-2 main protease …

In Silico Investigation on the Interaction of Chiral Phytochemicals from Opuntia ficus-indica with SARS-CoV-2 Mpro

C Vicidomini, V Roviello, GN Roviello - Symmetry, 2021 - mdpi.com
Opuntia ficus-indica is a cactaceous plant native to America but, nowadays, widely found
worldwide, having been the most common domesticated species of cactus grown as a crop …

A strategy for evaluating potential antiviral resistance to small molecule drugs and application to SARS-CoV-2

K Sargsyan, K Mazmanian, C Lim - Scientific Reports, 2023 - nature.com
Alterations in viral fitness cannot be inferred from only mutagenesis studies of an isolated
viral protein. To-date, no systematic analysis has been performed to identify mutations that …

Repurposing of FDA‐approved drugs against active site and potential allosteric drug‐binding sites of COVID‐19 main protease

M Yuce, E Cicek, T Inan, AB Dag… - Proteins: Structure …, 2021 - Wiley Online Library
The novel coronavirus disease 2019 (COVID‐19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) still has serious negative effects on health, social …

DFT, molecular docking and molecular dynamics simulation studies on some newly introduced natural products for their potential use against SARS-CoV-2

T Erdogan - Journal of Molecular Structure, 2021 - Elsevier
Throughout the history, natural products always give new paths to develop new drugs. As
with many other diseases, natural compounds can be helpful in the treatment of COVID-19 …

[HTML][HTML] Phytochemicals against SARS-CoV as potential drug leads

SS Swain, SK Panda, W Luyten - Biomedical Journal, 2021 - Elsevier
The newly emerged SARS-CoV-2 strains from the coronavirus (CoV) family is causing one
of the most disruptive pandemics of the past century. Developing antiviral drugs is a …

Targeting multiple conformations of SARS-CoV2 Papain-Like Protease for drug repositioning: An in-silico study

MI Ismail, HM Ragab, AA Bekhit, TM Ibrahim - Computers in biology and …, 2021 - Elsevier
Abstract Papain-Like Protease (PLpro) is a key protein for SARS-CoV-2 viral replication
which is the cause of the emerging COVID-19 pandemic. Targeting PLpro can suppress viral …