Human dendritic cells: their heterogeneity and clinical application potential in cancer immunotherapy
TA Patente, MP Pinho, AA Oliveira… - Frontiers in …, 2019 - frontiersin.org
Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …
T cell activation and effector differentiation. They are, likewise, involved in the induction and …
Vaccine delivery systems toward lymph nodes
Y Ding, Z Li, A Jaklenec, Q Hu - Advanced drug delivery reviews, 2021 - Elsevier
Strategies of improving vaccine targeting ability toward lymph nodes have been attracting
considerable interest in recent years, though there are remaining delivery barriers based on …
considerable interest in recent years, though there are remaining delivery barriers based on …
Dendritic cell-derived exosomes may be a tool for cancer immunotherapy by converting tumor cells into immunogenic targets
GG Romagnoli, BB Zelante, PA Toniolo… - Frontiers in …, 2015 - frontiersin.org
Dendritic cells (DCs) have been attracting attention in cancer immunotherapy because of
their role in inducing and modulating effective immune responses. Besides the direct contact …
their role in inducing and modulating effective immune responses. Besides the direct contact …
Trial watch: Dendritic cell-based interventions for cancer therapy
Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …
repertoire of responses that span from the development of self-tolerance to the elicitation of …
Phase I/II study of vaccination with electrofused allogeneic dendritic cells/autologous tumor-derived cells in patients with stage IV renal cell carcinoma
In the present study, we assessed the feasibility, toxicity, immunologic response, and clinical
efficacy of vaccination with allogeneic dendritic cell (DC)/tumor fusions in patients with …
efficacy of vaccination with allogeneic dendritic cell (DC)/tumor fusions in patients with …
Adjuvant vaccination with allogenic dendritic cells significantly prolongs overall survival in high-grade gliomas: Results of a phase II trial
Simple Summary Among all intracranial tumors, 31.5% are malignant, and among those,
glioblastomas account for 47%. Recently, our group reported the case of a patient with …
glioblastomas account for 47%. Recently, our group reported the case of a patient with …
Monocyte-derived dendritic cells from breast cancer patients are biased to induce CD4+CD25+Foxp3+ regulatory T cells
RN Ramos, LS Chin, APSA Dos Santos… - Journal of leukocyte …, 2012 - academic.oup.com
Immune deviation induced by breast cancer may have a role in current failures of dendritic
cell-based immunotherapy. DCs orchestrate immune responses contributing to the pattern of …
cell-based immunotherapy. DCs orchestrate immune responses contributing to the pattern of …
Vaccine therapy in patients with renal cell carcinoma
H Van Poppel, S Joniau, SW Van Gool - European Urology, 2009 - Elsevier
CONTEXT: Renal cell carcinoma (RCC) is one of the most immunoresponsive cancers in
humans. Although immunotherapy is currently much less used than in the past, it remains an …
humans. Although immunotherapy is currently much less used than in the past, it remains an …
[HTML][HTML] Pattern response of dendritic cells in the tumor microenvironment and breast cancer
A da Cunha, MA Michelin, EFC Murta - World journal of clinical …, 2014 - ncbi.nlm.nih.gov
Breast cancer (BC) is the most common malignant neoplasm and the cause of death by
cancer among women worldwide. Its development, including malignancy grade and patient …
cancer among women worldwide. Its development, including malignancy grade and patient …
Immunotherapy for renal cell carcinoma
M Itsumi, K Tatsugami - Journal of Immunology Research, 2010 - Wiley Online Library
Immunotherapy plays a significant role in the management of renal cell carcinoma (RCC)
patients with metastatic disease because RCC is highly resistant to both chemotherapy and …
patients with metastatic disease because RCC is highly resistant to both chemotherapy and …