Occurrence, classification, and biological function of hydrogenases: an overview

PM Vignais, B Billoud - Chemical reviews, 2007 - ACS Publications
If the atmosphere of the early Earth was hydrogen-rich, 1 it is reasonable to think that
hydrogenases, the enzymes enabling cells to use molecular hydrogen, were probably …

[HTML][HTML] The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism

R Lill, B Hoffmann, S Molik, AJ Pierik… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Mitochondria play a key role in iron metabolism in that they synthesize heme, assemble iron–
sulfur (Fe/S) proteins, and participate in cellular iron regulation. Here, we review the latter …

[HTML][HTML] Reprint of: Iron/sulfur proteins biogenesis in prokaryotes: formation, regulation and diversity

B Roche, L Aussel, B Ezraty, P Mandin, B Py… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Iron/sulfur centers are key cofactors of proteins intervening in multiple conserved cellular
processes, such as gene expression, DNA repair, RNA modification, central metabolism and …

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

DR Richardson, DJR Lane… - Proceedings of the …, 2010 - National Acad Sciences
The mitochondrion is well known for its key role in energy transduction. However, it is less
well appreciated that it is also a focal point of iron metabolism. Iron is needed not only for …

Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases

R Lill, U Mühlenhoff - Annu. Rev. Biochem., 2008 - annualreviews.org
Iron-sulfur (Fe/S) proteins are involved in a wide variety of cellular processes such as
enzymatic reactions, respiration, cofactor biosynthesis, ribosome biogenesis, regulation of …

Oxidative stress and iron homeostasis: mechanistic and health aspects

D Galaris, K Pantopoulos - Critical reviews in clinical laboratory …, 2008 - Taylor & Francis
Iron is an essential cofactor for important biological activities and biochemical reactions,
including the transport of oxygen via red blood cells and its reduction to water during …

Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes

JM Cameron, A Janer, V Levandovskiy… - The American Journal of …, 2011 - cell.com
Severe combined deficiency of the 2-oxoacid dehydrogenases, associated with a defect in
lipoate synthesis and accompanied by defects in complexes I, II, and III of the mitochondrial …

Fe-S cluster assembly pathways in bacteria

C Ayala-Castro, A Saini, FW Outten - Microbiology and Molecular …, 2008 - Am Soc Microbiol
SUMMARY Iron-sulfur (Fe-S) clusters are required for critical biochemical pathways,
including respiration, photosynthesis, and nitrogen fixation. Assembly of these iron cofactors …

Mitochondrial iron metabolism and neurodegenerative diseases

R Cheng, VV Dhorajia, J Kim, Y Kim - Neurotoxicology, 2022 - Elsevier
Iron is a key element for mitochondrial function and homeostasis, which is also crucial for
maintaining the neuronal system, but too much iron promotes oxidative stress. A large body …

Advanced biofuel production by the yeast Saccharomyces cerevisiae

NA Buijs, V Siewers, J Nielsen - Current opinion in chemical biology, 2013 - Elsevier
Replacement of conventional transportation fuels with biofuels will require production of
compounds that can cover the complete fuel spectrum, ranging from gasoline to kerosene …