Approximately 4% of cancers worldwide are caused by alcohol consumption. Drinking
alcohol increases the risk of several cancer types, including cancers of the upper …

Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

Aims To evaluate the impact of galangin treatment on cerebral ischemia-reperfusion (I/R)
injury in gerbils and to identify potential mechanisms of the protective effect of galangin on …

Objective Cerebral ischemia is the most common type of neuronal injury and is
characterized by a reduction in the function and number of hippocampal neurons. Carvacrol …

Alcohol use disorder (AUD) is a highly prevalent, comorbid, and disabling disorder. The
underlying mechanism of ethanol neurotoxicity and the involvement of oxidative stress is still …

This paper reviews the body of evidence that major depression is accompanied by a
decreased antioxidant status and by induction of oxidative and nitrosative (IO&NS) …

In some patients with major depressive disorder (MDD), individual illness characteristics
appear consistent with those of a neuroprogressive illness. Features of neuroprogression …

Background Blau theorized that migraine triggers are exposures that in higher amounts
would damage the brain. The recent discovery that the TRPA1 ion channel transduces …

Toll-like receptors play an important role in the innate immune response, although emerging
evidence indicates their role in brain injury and neurodegeneration. Alcohol abuse induces …

Oxidative stress has been implicated in the pathogenesis of neurologic and psychiatric
diseases. The brain is particularly vulnerable to oxidative damage due to high oxygen …