Polyphosphoinositide binding domains: Key to inositol lipid biology
GRV Hammond, T Balla - Biochimica Et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Polyphosphoinositides (PPIn) are an important family of phospholipids located on the
cytoplasmic leaflet of eukaryotic cell membranes. Collectively, they are critical for the …
cytoplasmic leaflet of eukaryotic cell membranes. Collectively, they are critical for the …
Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration
D Križaj, S Cordeiro, O Strauß - Progress in Retinal and eye Research, 2023 - Elsevier
Transient receptor potential (TRP) channels are a widely expressed family of 28
evolutionarily conserved cationic ion channels that operate as primary detectors of chemical …
evolutionarily conserved cationic ion channels that operate as primary detectors of chemical …
TRPV1 channels are intrinsically heat sensitive and negatively regulated by phosphoinositide lipids
E Cao, JF Cordero-Morales, B Liu, F Qin, D Julius - Neuron, 2013 - cell.com
The capsaicin receptor, TRPV1, is regulated by phosphatidylinositol-4, 5-bisphosphate (PIP
2), although the precise nature of this effect (ie, positive or negative) remains controversial …
2), although the precise nature of this effect (ie, positive or negative) remains controversial …
[HTML][HTML] Genetic manipulation of genes and cells in the nervous system of the fruit fly
Research in the fruit fly Drosophila melanogaster has led to insights in neural development,
axon guidance, ion channel function, synaptic transmission, learning and memory, diurnal …
axon guidance, ion channel function, synaptic transmission, learning and memory, diurnal …
Activation of TRP channels by protons and phosphoinositide depletion in Drosophila photoreceptors
J Huang, CH Liu, SA Hughes, M Postma… - Current Biology, 2010 - cell.com
Background Phototransduction in microvillar photoreceptors is mediated via G protein-
coupled phospholipase C (PLC), but how PLC activation leads to the opening of the light …
coupled phospholipase C (PLC), but how PLC activation leads to the opening of the light …
TRP channels and lipids: from Drosophila to mammalian physiology
RC Hardie - The Journal of physiology, 2007 - Wiley Online Library
The transient receptor potential (TRP) ion channel family was the last major ion channel
family to be discovered. The prototypical member (dTRP) was identified by a forward genetic …
family to be discovered. The prototypical member (dTRP) was identified by a forward genetic …
Fundamental role of microvilli in the main functions of differentiated cells: Outline of an universal regulating and signaling system at the cell periphery
K Lange - Journal of cellular physiology, 2011 - Wiley Online Library
Until now, the general importance of microvilli present on the surface of almost all
differentiated cells has been strongly underestimated and essential functions of these …
differentiated cells has been strongly underestimated and essential functions of these …
Endothelial TRPV4 channels modulate vascular tone by Ca2+‐induced Ca2+ release at inositol 1,4,5‐trisphosphate receptors
Background and Purpose The TRPV4 ion channels are Ca2+ permeable, non‐selective
cation channels that mediate large, but highly localized, Ca2+ signals in the endothelium …
cation channels that mediate large, but highly localized, Ca2+ signals in the endothelium …
Regulation of membrane turnover by phosphatidic acid: cellular functions and disease implications
Phosphatidic acid (PA) is a simple glycerophospholipid with a well-established role as an
intermediate in phospholipid biosynthesis. In addition to its role in lipid biosynthesis, PA has …
intermediate in phospholipid biosynthesis. In addition to its role in lipid biosynthesis, PA has …