Obesity I: Overview and molecular and biochemical mechanisms

RH Lustig, D Collier, C Kassotis, TA Roepke… - Biochemical …, 2022 - Elsevier
Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …

Machine learning based diabetes classification and prediction for healthcare applications

UM Butt, S Letchmunan, M Ali… - Journal of healthcare …, 2021 - Wiley Online Library
The remarkable advancements in biotechnology and public healthcare infrastructures have
led to a momentous production of critical and sensitive healthcare data. By applying …

Type 2 diabetes in children and adolescents: distinct characteristics and evidence-based management

K Karavanaki, SA Paschou, N Tentolouris… - Endocrine, 2022 - Springer
Purpose Since the dramatic rise of obesity prevalence in childhood and adolescence has
contributed to increased rates of type 2 diabetes (T2D) in youth, we sought to explore current …

[HTML][HTML] Cardiometabolic risk factors and metabolic syndrome based on severity of obesity in Korean children and adolescents: data from the Korea National Health …

M Kim, J Kim - Annals of Pediatric Endocrinology & Metabolism, 2022 - ncbi.nlm.nih.gov
Purpose Data regarding cardiometabolic risk factors (CMRFs) and metabolic syndrome
(MetS) by body mass index (BMI) category in Korean youth are sparse. Methods Among the …

[HTML][HTML] Changes in the prevalences of obesity, abdominal obesity, and non-alcoholic fatty liver disease among Korean children during the COVID-19 outbreak

K Song, J Yang, HS Lee, SJ Kim, M Lee… - Yonsei Medical …, 2023 - ncbi.nlm.nih.gov
Purpose We aimed to investigate the prevalences of obesity, abdominal obesity, and non-
alcoholic fatty liver disease (NAFLD) among children and adolescents during the …

[HTML][HTML] Associations between food portion sizes, insulin resistance, VO2 max and metabolic syndrome in European adolescents: The HELENA study

SM Flieh, ML Miguel-Berges, I Huybrechts… - Nutrition, Metabolism …, 2022 - Elsevier
Background and aims This study aims to examine the associations of food portion size (PS)
with markers of insulin resistance (IR) and clustered of metabolic risk score in European …

Metabolite signature of physical activity and the risk of type 2 diabetes in 7271 men

SM Kemppainen, L Fernandes Silva, MA Lankinen… - Metabolites, 2022 - mdpi.com
Large population-based studies investigating the association of physical activity (PA) with
the metabolite signature contribute significantly to the understanding of the effects of PA on …

Insulin Dynamics and Pathophysiology in Youth-Onset Type 2 Diabetes

R Abu-Nejem, TS Hannon - The Journal of Clinical …, 2024 - academic.oup.com
Youth-onset type 2 diabetes (T2D) is increasing around the globe. The mounting disease
burden of youth-onset T2D portends substantial consequences for the health outcomes of …

Reassessing type 2 diabetes in adolescents and its management strategies based on insulin resistance

QY Jia, YM Zhang, BF Zhang, XD An - Frontiers in Endocrinology, 2024 - frontiersin.org
With changes in lifestyle behaviors, including dietary structure and habits, the prevalence of
Youth-onset Type 2 Diabetes Mellitus (YODM) has increased 2 to 3 times compared to 30 …

Changes in OGTT‐derived biomarkers in response to lifestyle intervention among Latino adolescents with obesity

A Peña, JY Kim, JA Reyes, KB Vander Wyst… - Pediatric …, 2022 - Wiley Online Library
Background Glucose concentrations during an oral glucose tolerance test (OGTT) have
been used as biomarkers to differentiate type 2 diabetes risk phenotypes. No studies have …