In the last two decades major changes have occurred in how microbial ecologists study
microbial communities. Limitations associated with traditional culture-based methods have …

The parts of the genome transcribed by a cell or tissue reflect the biological processes and
functions it carries out. We characterized the features of mammalian tissue transcriptomes at …

Evolutionary developmental biology has grown historically from the capacity to relate
patterns of evolution in anatomy to patterns of evolution of expression of specific genes …

Because mouse models play a crucial role in biomedical research related to the human
nervous system, understanding the similarities and differences between mouse and human …

Genetic changes affecting gene expression contribute to phenotypic divergence; thus,
understanding how regulatory networks controlling gene expression change over time is …

One-to-one orthologous genes of relatively closely related species are widely assumed to
have similar functions and cause similar phenotypes when deleted from the genome …

Various databases have harnessed the wealth of publicly available microarray data to
address biological questions ranging from across-tissue differential expression to …

The traditional approach for estimating noncancer and cancer reference values in
quantitative chemical risk assessment is time and resource intensive. The extent and nature …

Background It is widely accepted that orthologous genes between species are conserved at
the sequence level and perform similar functions in different organisms. However, the level …

Abstract Background Aspartic proteases (APs) are a large family of proteolytic enzymes
found in almost all organisms. In plants, they are involved in many biological processes …