Interindividual variability in response to drugs used in anesthesia has long been considered
the rule, not the exception. It is important to mention that in anesthesiology, the variability in …

Successful pain management requires the delivery of analgesia with minimal risk of adverse
drug reactions. Nonsteroidal anti-inflammatory drugs and opioids remain the mainstay of …

Background: Gastroscopy is one of the most commonly used diagnostic modalities for upper
gastrointestinal disorders. Remazolam besylate, a new type of ultrashort-acting …

Results Analysis of all the targeted DNA sequences for the whole patient group indicated
121 different functional variants. After association analyses of 31 selected variants, the …

OBJECTIVE: Propofol (2, 6-diisopropylphenol) is a broadly used anaesthetic in total
intravenous anaesthesia (TIVA) that might alter course of disease in patients who underwent …

Background The aim of this study was to investigate the effect of CYB2B6 (c. 516G> T,
rs3745274), CYP2C9 (c. 1075A> C, rs1057910) and UGT1A9 (c. 98T> C, rs72551330) …

ABSTRACT Propofol (2, 6-diisopropylphenol) is the most common intravenous anesthetic
used in modern medicine. It is postulated that individual differences in genetic factors …

Rocuronium and propofol are widely used intravenous anaesthesia drugs during general
anaesthesia. Dosing is mostly based on weight with great inter-individual variation in …

Background Gastroscopy is one of the most commonly used diagnostic modalities for upper
gastrointestinal disorders. Remazolam besylate, a new type of ultra-short-acting …

We live in a world where the pharmaceutical industry is experiencing its rise and attention,
and every day we face different reactions, different response to different drugs in different …