A comprehensive account on recent progress in pharmacological activities of benzimidazole derivatives
Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest
among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole …
among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole …
Current trends in computational quantum chemistry studies on antioxidant radical scavenging activity
M Spiegel - Journal of Chemical Information and Modeling, 2022 - ACS Publications
The antioxidative nature of chemicals is now routinely studied using computational quantum
chemistry. Scientists are constantly proposing new approaches to investigate those …
chemistry. Scientists are constantly proposing new approaches to investigate those …
A panoramic review of benzimidazole derivatives and their potential biological activity
H Hernández-López… - Mini Reviews in …, 2022 - ingentaconnect.com
The therapeutic potential of the benzimidazole nucleus has been recognized since 1944,
and it is an important heterocycle system due to its presence in a wide range of bioactive …
and it is an important heterocycle system due to its presence in a wide range of bioactive …
Study on the neuroprotective, radical-scavenging and MAO-B inhibiting properties of new benzimidazole arylhydrazones as potential multi-target drugs for the …
N Anastassova, D Aluani, N Hristova-Avakumova… - Antioxidants, 2022 - mdpi.com
Oxidative stress is a key contributing factor in the complex degenerating cascade in
Parkinson's disease. The inhibition of MAO-B affords higher dopamine bioavailability and …
Parkinson's disease. The inhibition of MAO-B affords higher dopamine bioavailability and …
Synthesis, Spectroscopic and Computational Analysis of 2-[(2-Sulfanyl-1H-benzo[d]imidazol-5-yl)iminomethyl]phenyl Naphthalene-2-sulfonate
G Kotan, H Gökce, O Akyıldırım, H Yüksek… - Russian Journal of …, 2020 - Springer
Abstract 2-[(2-Sulfanyl-1 H-benzo [d] imidazol-5-yl) iminomethyl] phenyl naphthalene-2-
sulfonate was obtained as a result of the reactions of 5-amino-2-sulfanylbenzimidazole with …
sulfonate was obtained as a result of the reactions of 5-amino-2-sulfanylbenzimidazole with …
How hydrogen bond interactions affect the flame retardancy and anti‐dripping performances of PET
YP Ni, WS Wu, L Chen, X Zhao, ZH Qin… - Macromolecular …, 2020 - Wiley Online Library
To systematically study how the H‐bonding interaction affect the flame retardancy and anti‐
dripping behavior of poly (ethylene terephthalate)(PET), two series of PET‐based …
dripping behavior of poly (ethylene terephthalate)(PET), two series of PET‐based …
Design, synthesis, antioxidant properties and mechanism of action of new N, N′-disubstituted benzimidazole-2-thione hydrazone derivatives
NO Anastassova, DY Yancheva, AT Mavrova… - Journal of Molecular …, 2018 - Elsevier
New series of N, N′-disubstituted benzimidazole-2-thione were synthesized by introduction
of hydrazone moiety in the side chains. The toxicological potential of studied compounds …
of hydrazone moiety in the side chains. The toxicological potential of studied compounds …
Evaluation of the combined activity of benzimidazole arylhydrazones as new anti-Parkinsonian agents: monoamine oxidase-B inhibition, neuroprotection and …
N Anastassova, D Aluani, A Kostadinov… - Neural Regeneration …, 2021 - journals.lww.com
Neuroprotective drugs and selective monoamine oxidase inhibitors can slow down the
progression and improve symptoms of Parkinson's disease (PD). Since there is an …
progression and improve symptoms of Parkinson's disease (PD). Since there is an …
One‐Pot Tandem Protocol for the Synthesis of 1, 3‐Bis (β‐aminoacrylate)‐Substituted 2‐Mercaptoimidazole Scaffolds
J Luo, GS Chen, SJ Chen, ZD Li… - … Synthesis & Catalysis, 2020 - Wiley Online Library
We have developed a palladium‐catalyzed cross‐coupling reaction of isocyanides with α‐
diazoacetates to form active ketenimines and following a 1, 4‐diazabicyclo [2.2. 2] octane …
diazoacetates to form active ketenimines and following a 1, 4‐diazabicyclo [2.2. 2] octane …
Design, synthesis, and biological activity studies on benzimidazole derivatives targeting myeloperoxidase
Myeloperoxidase (MPO) plays a key role in human antimicrobial system by oxidizing vital
molecules of microorganisms in phagolysosomes through produced hypochlorous acid …
molecules of microorganisms in phagolysosomes through produced hypochlorous acid …