Functional connectivity of amygdala subnuclei in PTSD: a narrative review
While the amygdala is often implicated in the neurobiology of posttraumatic stress disorder
(PTSD), the pattern of results remains mixed. One reason for this may be the heterogeneity …
(PTSD), the pattern of results remains mixed. One reason for this may be the heterogeneity …
The role of Serotonin in fear learning and memory: A systematic review of human studies
Fear is characterized by distinct behavioral and physiological responses that are essential
for the survival of the human species. Fear conditioning (FC) serves as a valuable model for …
for the survival of the human species. Fear conditioning (FC) serves as a valuable model for …
Laboratory models of post-traumatic stress disorder: The elusive bridge to translation
Post-traumatic stress disorder (PTSD) is a debilitating mental illness composed of a
heterogeneous collection of symptom clusters. The unique nature of PTSD as arising from a …
heterogeneous collection of symptom clusters. The unique nature of PTSD as arising from a …
Delivery of graphene oxide nanosheets modulates glutamate release and normalizes amygdala synaptic plasticity to improve anxiety-related behavior
Graphene oxide nanosheets (GO) were reported to alter neurobiological processes
involving cell membrane dynamics. GO ability to reversibly downregulate specifically …
involving cell membrane dynamics. GO ability to reversibly downregulate specifically …
Multiple factors contribute to flight behaviors during fear conditioning
T Furuyama, A Imayoshi, T Iyobe, M Ono, T Ishikawa… - Scientific Reports, 2023 - nature.com
Shifting defensive mode from one to another by the imminence of threat is crucial for
survival. The transition of defensive mode from freezing to flight is observed during the …
survival. The transition of defensive mode from freezing to flight is observed during the …
The neural circuits and molecular mechanisms underlying fear dysregulation in posttraumatic stress disorder
Post-traumatic stress disorder (PTSD) is a stress-associated complex and debilitating
psychiatric disorder due to an imbalance of neurotransmitters in response to traumatic …
psychiatric disorder due to an imbalance of neurotransmitters in response to traumatic …
Integrating threat conditioning and the hierarchical taxonomy of psychopathology to advance the study of anxiety-related psychopathology.
Theoretical and methodological research on threat conditioning provides important
neuroscience-informed approaches to studying fear and anxiety. The threat conditioning …
neuroscience-informed approaches to studying fear and anxiety. The threat conditioning …
[HTML][HTML] Pattern differentiation and tuning shift in human sensory cortex underlie long-term threat memory
The amygdala-prefrontal-cortex circuit has long occupied the center of the threat system, 1
but new evidence has rapidly amassed to implicate threat processing outside this canonical …
but new evidence has rapidly amassed to implicate threat processing outside this canonical …
Sex-dependent fear memory impairment in cocaine-sired rat offspring
MT Rich, SJ Worobey, S Mankame, ZP Pang… - Science …, 2023 - science.org
Cocaine self-administration by male rats results in neuronal and behavioral alterations in
offspring, including responses to cocaine. Given the high degree of overlap between the …
offspring, including responses to cocaine. Given the high degree of overlap between the …
Insulin-like growth factor I mitigates post-traumatic stress by inhibiting AMP-kinase in orexin neurons
ME Fernández de Sevilla, J Pignatelli… - Molecular …, 2022 - nature.com
Maladaptive coping behaviors are probably involved in post-traumatic stress disorders
(PTSD), but underlying mechanisms are incompletely understood. We now report that mice …
(PTSD), but underlying mechanisms are incompletely understood. We now report that mice …