Chrysin belongs to the group of natural polyphenols. It can be found, among others, in
honey, propolis and fruits and has a wide range of biological activities, including the …

The supercritical antisolvent (SAS) technique has been widely employed in the biomedical
field, including drug delivery, to obtain drug particles or polymer-based systems of …

Despite the success in developing various pharmaceutical formulations, most of the active
pharmaceutical ingredients (APIs)/drugs, according to the Biopharmaceutics Classification …

Poor bioavailability and aqueous solubility represent a major constraint during the
development of new API molecules and can influence the impact of new medicines or halt …

Solid multicomponent systems (SMS) are gaining an increasingly important role in the
pharmaceutical industry, to improve the physicochemical properties of active pharmaceutical …

Supercritical CO 2 techniques are promising technologies for developing products that can
be useful for biomedical engineering. However, the obtained products (aerogels, foams …

Hesperetin (HST) is a bioflavonoid from citrus fruits and its clinical application is still
markedly limited by its poor water solubility (1.27 µg/mL). Herein, a complex nanoparticle …

Despite significant advances in drug formulation, the clinical application of most active
pharmaceutical ingredients from traditional Chinese herbs remained a significant challenge …

Nanomaterials doped with non-metallic C have attracted tremendous attention as potential
nano-artificial enzymes due to their ability to change the energy band structure to improve …

The low aqueous solubility and subsequently slow dissolution rate, as well as the poor
bioavailability of several active pharmaceutical ingredients (APIs), are major challenges in …