Proteogenomics of different urothelial bladder cancer stages reveals distinct molecular features for papillary cancer and carcinoma in situ
Z Yao, N Xu, G Shang, H Wang, H Tao, Y Wang… - Nature …, 2023 - nature.com
The progression of urothelial bladder cancer (UC) is a complicated multi-step process. We
perform a comprehensive multi-omics analysis of 448 samples from 190 UC patients …
perform a comprehensive multi-omics analysis of 448 samples from 190 UC patients …
Targeting the “undruggable”: rNA-binding proteins in the spotlight in cancer therapy
C Mir, Y Garcia-Mayea, ME Lleonart - Seminars in Cancer Biology, 2022 - Elsevier
Tumors refractory to conventional therapy belong to specific subpopulations of cancer cells,
which have acquired a higher number of mutations/epigenetic changes than the majority of …
which have acquired a higher number of mutations/epigenetic changes than the majority of …
SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation
TT Gong, FH Liu, Q Xiao, YZ Li, YF Wei, HL Xu… - Communications …, 2024 - nature.com
Platinum-based chemotherapy remains one of the major choices for treatment of ovarian
cancer (OC). However, primary or acquired drug resistance severely impairs their efficiency …
cancer (OC). However, primary or acquired drug resistance severely impairs their efficiency …
Increased expression of the RBPMS splice variants inhibits cell proliferation in ovarian cancer cells
RJ Rabelo-Fernández, RA Noriega Rivera… - International Journal of …, 2022 - mdpi.com
RNA-Binding Protein with Multiple Splicing (RBPMS) is a member of family proteins that
bind to nascent RNA transcripts and regulate their splicing, localization, and stability …
bind to nascent RNA transcripts and regulate their splicing, localization, and stability …
Loss of RBPMS in ovarian cancer compromises the efficacy of EGFR inhibitor gefitinib through activating HER2/AKT/mTOR/P70S6K signaling
M Li, M Hu, Y Wang, Z Xia, Z Li, J Li, D Zheng… - Biochemical and …, 2022 - Elsevier
RBPMS may be a tumor suppressor in cancer, but its impact in modulation of drug sensitivity
is unclear. This study aimed to investigate the regulatory role of RBPMS in cellular response …
is unclear. This study aimed to investigate the regulatory role of RBPMS in cellular response …
Proteogenomic characterization of the non-muscle-invasive bladder cancer response to BCG reveals potential therapeutic strategies
Y Qu, N Xu, Z Yao, L Zhang, Y Zhu, T Cai, Y Wang, K Li… - 2024 - researchsquare.com
Background Intravesical bacillus Calmette-Guérin (BCG) is the standard therapy for adjuvant
treatment in patients with intermediate-and high-risk superficial bladder cancer. However …
treatment in patients with intermediate-and high-risk superficial bladder cancer. However …
Unraveling the role of RNA Binding Protein with Multiple Splicing (RBPMS) in ovarian cancer cells
RJ Rabelo Fernández - 2023 - repositorio.upr.edu
RNA-Binding Protein with Multiple Splicing (RBPMS) is member of a family of proteins that
bind to nascent RNA transcripts and regulate their splicing, localization, and stability …
bind to nascent RNA transcripts and regulate their splicing, localization, and stability …
[引用][C] ANÁLISIS DE UN PERFIL DE EXPRESIÓN GÉNICA COMÚN ENTRE ENFERMEDAD PULMONAR INTERSTICIAL FIBROSANTE Y CÁNCER DE PULMÓN DE …
MAI Orozco - PONTIFICIA UNIVERSIDAD …