Drug resistance and treatment failure in leishmaniasis: A 21st century challenge
A Ponte-Sucre, F Gamarro, JC Dujardin… - PLoS neglected …, 2017 - journals.plos.org
Reevaluation of treatment guidelines for Old and New World leishmaniasis is urgently
needed on a global basis because treatment failure is an increasing problem. Drug …
needed on a global basis because treatment failure is an increasing problem. Drug …
Evolutionary Emergence of Drug Resistance in Candida Opportunistic Pathogens
E Ksiezopolska, T Gabaldón - Genes, 2018 - mdpi.com
Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …
medical concern. In developed countries, the incidence of Candida infections is increasing …
An Update on Candida tropicalis Based on Basic and Clinical Approaches
DL Zuza-Alves, WP Silva-Rocha… - Frontiers in …, 2017 - frontiersin.org
Candida tropicalis has emerged as one of the most important Candida species. It has been
widely considered the second most virulent Candida species, only preceded by C. albicans …
widely considered the second most virulent Candida species, only preceded by C. albicans …
Collateral sensitivity counteracts the evolution of antifungal drug resistance in Candida auris
H Carolus, D Sofras, G Boccarella, S Jacobs… - Nature …, 2024 - nature.com
Antifungal drug resistance represents a serious global health threat, necessitating new
treatment strategies. Here we investigated collateral sensitivity (CS), in which resistance to …
treatment strategies. Here we investigated collateral sensitivity (CS), in which resistance to …
Fungal cell wall: emerging antifungals and drug resistance
SL Lima, AL Colombo… - Frontiers in microbiology, 2019 - frontiersin.org
The cell wall is an essential component in fungal homeostasis. The lack of a covering wall in
human cells makes this component an attractive target for antifungal development. The host …
human cells makes this component an attractive target for antifungal development. The host …
The quiet and underappreciated rise of drug-resistant invasive fungal pathogens
A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …
[HTML][HTML] Susceptibility test for fungi: clinical and laboratorial correlations in medical mycology
A Alastruey-Izquierdo, MSC Melhem… - Revista do Instituto de …, 2015 - SciELO Brasil
During recent decades, antifungal susceptibility testing has become standardized and
nowadays has the same role of the antibacterial susceptibility testing in microbiology …
nowadays has the same role of the antibacterial susceptibility testing in microbiology …
Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical …
TR Rogers, PE Verweij, M Castanheira… - Journal of …, 2022 - academic.oup.com
The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …
to present many challenges to their effective management. The repertoire of antifungal drugs …
Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus
SS Gonçalves, ACR Souza, A Chowdhary, JF Meis… - Mycoses, 2016 - Wiley Online Library
The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …
New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics
J Geddes‐McAlister, RS Shapiro - … of the New York Academy of …, 2019 - Wiley Online Library
Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
becomes increasingly common, fungal infections are becoming more prevalent. The use of …