Radiation‐induced myocardial fibrosis (RIMF) is a potentially lethal clinical complication of
chest radiotherapy (RT) and a final stage of radiation‐induced heart disease (RIHD). RIMF is …

Radiotherapy may be used alone or in combination with chemotherapy for cancer treatment.
There are many mechanisms of radiation treatment exposure to toxicities. Our aim was to …

Simple Summary Side effects caused by the concomitant irradiation of normal tissue during
radiotherapy for cancer treatment can negatively affect the patient's quality of life and limit …

Background and purpose The effects of radiation on the heart are dependent on dose,
fractionation, overall treatment time, and pre-existing cardiovascular pathology. Murine …

Purpose Radiation-induced lung injury is a major dose-limiting toxicity for thoracic radiation
therapy patients. In experimental models, treatment with angiotensin converting enzyme …

Cancer patients undergoing radiotherapy, chemotherapy, or targeted cancer therapy are
exposed to the risk of several side effects because of the heavy production of ROS by …

This Roadmap paper covers the field of precision preclinical x-ray radiation studies in
animal models. It is mostly focused on models for cancer and normal tissue response to …

Background and purpose Radiation-induced cardiac toxicity (RICT) remains one of the most
critical dose limiting constraints in radiotherapy. Recent studies have shown higher doses to …

Background Rapidly dividing cells are more sensitive to radiation therapy (RT) than
quiescent cells. In the failing myocardium, macrophages and fibroblasts mediate collateral …

Simple Summary The objective of the present study was to investigate the impact of sex in
the development of long-term toxicities affecting quality of life in cancer survivors after …